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对于低渗肿胀试验分数较低的男性,即使伴有极低的精子活力百分比,卵胞浆内单精子注射也能获得正常的妊娠率。

Intracytoplasmic sperm injection allows normal pregnancy rates for males 40 with low hypoosmotic swelling test scores even when complicated by very low motility percentage.

作者信息

Check J H, Tubman A, Wilson C

机构信息

The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, SA.

出版信息

Clin Exp Obstet Gynecol. 2013;40(1):18-9.

PMID:23724495
Abstract

PURPOSE

To determine if the additional burden of low percentage motility reduces the chance that sperm with low hypoosmotic swelling (HOS) test scores will achieve a pregnancy following in vitro fertilization (IVF) with intracytoplasmic sperm injections (ICSI).

METHODS

Couples undergoing IVF-embryo transfer (ET) and ICSI for low HOS tests (< 50%) were retrospectively identified. The percentage motility was divided into deciles. Pregnancy rates were determined according to the deciles of motility.

RESULTS

No differences in clinical or live delivered pregnancy rates per transfer were found in even the very lowest percent motility category.

CONCLUSIONS

The added complicating factor of low percentage motility added to sperm with low HOS test scores does not reduce the effectiveness of IVF with ICSI.

摘要

目的

确定低活动率这一额外负担是否会降低低低渗肿胀试验(HOS)评分的精子在卵胞浆内单精子注射(ICSI)体外受精(IVF)后实现妊娠的几率。

方法

回顾性确定因低HOS试验(<50%)而接受IVF-胚胎移植(ET)和ICSI的夫妇。将活动率百分比分为十分位数。根据活动率的十分位数确定妊娠率。

结果

即使在活动率百分比非常低的类别中,每次移植的临床妊娠率或活产妊娠率也没有差异。

结论

低活动率这一额外的复杂因素加在低HOS试验评分的精子上,并不会降低ICSI-IVF的有效性。

相似文献

1
Intracytoplasmic sperm injection allows normal pregnancy rates for males 40 with low hypoosmotic swelling test scores even when complicated by very low motility percentage.对于低渗肿胀试验分数较低的男性,即使伴有极低的精子活力百分比,卵胞浆内单精子注射也能获得正常的妊娠率。
Clin Exp Obstet Gynecol. 2013;40(1):18-9.
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Effect of poor motility on pregnancy outcome following intracytoplasmic sperm injection in couples whose male partners have subnormal hypo-osmotic swelling test scores.男性伴侣低渗肿胀试验评分低于正常水平的夫妇,其精子活力差对卵胞浆内单精子注射后妊娠结局的影响。
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Sperm with an abnormal hypo-osmotic swelling test--normal fertilization, normal embryo development, but implantation failure.低渗肿胀试验异常的精子——受精正常、胚胎发育正常,但着床失败。
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About 13% of women may have the wrong method of oocyte insemination when undergoing in vitro fertilization by failure to evaluate the abnormal hypo-osmotic swelling test score.在接受体外受精时,约13%的女性可能因未评估异常低渗肿胀试验评分而采用错误的卵母细胞授精方法。
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Intracytoplasmic sperm injection completely negates the implantation problem associated with conventional fertilization with sperm with low hypo-osmotic swelling test scores as evidenced by evaluating donor-recipient pairs.通过对供体-受体配对进行评估可知,卵胞浆内单精子注射完全消除了与传统受精相关的植入问题,传统受精采用的精子低渗肿胀试验得分较低。
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Anti-sperm antibody levels are not related to fertilization or pregnancy rates after IVF or IVF/ICSI.抗精子抗体水平与 IVF 或 IVF/ICSI 后的受精率或妊娠率无关。
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In vitro fertilization with intracytoplasmic sperm injection is an effective therapy for male factor infertility related to subnormal hypo-osmotic swelling test scores.卵胞浆内单精子注射体外受精是治疗与低渗肿胀试验评分低于正常相关的男性因素不孕症的有效方法。
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引用本文的文献

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Comparison of intracytoplasmic sperm injection outcome with fresh versus frozen-thawed testicular sperm in men with nonobstructive azoospermia: a systematic review and meta-analysis.比较非梗阻性无精子症患者新鲜与冻融睾丸精子行卵胞浆内单精子注射结局:系统评价和荟萃分析。
J Assist Reprod Genet. 2018 Jul;35(7):1247-1257. doi: 10.1007/s10815-018-1206-5. Epub 2018 May 21.