Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
Org Lett. 2011 May 6;13(9):2448-51. doi: 10.1021/ol2006902. Epub 2011 Apr 12.
A novel cationic Br initiated one-pot imidazoline synthesis has been developed using olefin, nitrile, amine, and N-bromosuccinimide. The olefinic substrates and the nitrile partners can be flexibly varied to achieve a range of imidazoline derivatives.
开发了一种新型阳离子 Br 引发的一锅法咪唑啉合成方法,使用烯烃、腈、胺和 N-溴代丁二酰亚胺。可以灵活改变烯烃底物和腈配体,以获得一系列咪唑啉衍生物。