Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
Org Lett. 2011 Dec 16;13(24):6456-9. doi: 10.1021/ol202751s. Epub 2011 Nov 16.
A one-pot electrophilic alkoxyetherification using an olefin, a cyclic ether, a carboxylic acid, and N-bromosuccinimide has been developed. The oxygen nucleophiles, the olefinic substrates, and the cyclic ether partners can be varied to produce a wide range of alkoxyether derivatives.
发展了一种通过烯烃、环醚、羧酸和 N-溴代丁二酰亚胺一锅法进行的亲电烷氧基醚化反应。可以改变亲核氧试剂、烯烃底物和环醚伙伴,以产生广泛的烷氧基醚衍生物。