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掌腱膜挛缩症:回顾性数据库分析评估英国的临床管理和费用。

Dupuytren's contracture: a retrospective database analysis to assess clinical management and costs in England.

机构信息

Clinical Development and Medical Affairs, Pfizer Global Development Headquarters, New London, CT, USA.

出版信息

BMC Musculoskelet Disord. 2011 Apr 12;12:73. doi: 10.1186/1471-2474-12-73.

Abstract

BACKGROUND

Dupuytren's disease is a fibro-proliferative disorder affecting ~3-5% of the UK population. Current surgical treatments for Dupuytren's contracture (DC) include fasciectomy and fasciotomy. We assessed the clinical management of DC in England over a 5-year period; associated NHS costs were assessed for a 1-year period.

METHODS

Hospital Episode Statistics were extracted from April 2003 to March 2008 for patients with Palmar Fascial Fibromatosis (ICD10=M720) and DC-related procedures. Variables included demographics, OPCS, patient status and physician specialty. To estimate 2010-2011 costs, HRG4 codes and the National Schedule of Tariff 2010-11-NHS Trusts were applied to the 2007-2008 period.

RESULTS

Over 5 years, 75,157 DC admissions were recorded; 64,506 were analyzed. Mean admissions per year were 12,901 and stable. Day cases increased from 42% (2003-2004) to 62% (2007-2008). The percent of patients having two or more admissions per year increased from 5.5% in 2003-2004 to 26.1% in 2007-2008. Between 2003 and 2007, 91% of procedures were Fasciectomy. Revision of Fasciectomy and Fasciotomy each accounted for ~4%; Amputation for 1%. In 2007, classification was extended to identify Digital Fasciectomy, its Revision and Dermofasciectomy. In 2007-2008, admissions were: 70% Palmar Fasciectomy, 16% Digital Fasciectomy, 1.3% Other Fasciectomy, 4.4% Revision of Palmar Fasciectomy, 1.3% Revision of Digital Fasciectomy, 3.8% Division of Palmar Fascia, 2.6% Dermofasciectomy and 1.1% Amputation. 79% of cases were overseen by trauma and orthopaedic surgeons, 19% by plastic surgeons. Mean (±SD) inpatient hospital length of stay was 1.5 (±1.4) days in 2003-2004 and 1.0 (±1.3) days in 2007-2008. Total estimated costs for 1 year (2010-2011) were £41,576,141. Per-patient costs were £2,885 (day case) and £3,534 (inpatient). Costs ranged from £2,736 (day-case Fasciectomy) to £9,210 (day-case Revision Digital).

CONCLUSIONS

Between 2003 and 2008, fasciectomy was the most common surgical procedure for DC in England. While procedure rates and physician specialties varied little, there was a reversal in surgical venue: inpatient operations decreased as day-case procedures increased. The change is likely due to economic trends and changes to the healthcare system. Estimated costs for 2010-2011 varied by procedure type and patient status. These findings can be used to understand clinical management of DC and guide healthcare policy.

摘要

背景

掌腱膜挛缩症是一种纤维增生性疾病,影响英国人口的 3-5%。目前治疗掌腱膜挛缩症(Dupuytren 挛缩)的手术方法包括筋膜切开术和筋膜切除术。我们评估了 5 年内英格兰对掌腱膜挛缩症的临床治疗管理;对 1 年内的 NHS 相关费用进行了评估。

方法

从 2003 年 4 月至 2008 年 3 月,提取患有掌腱膜纤维瘤(ICD10=M720)和掌腱膜挛缩相关手术的患者的医院入院记录。变量包括人口统计学、OPCS、患者状态和医生专业。为了估计 2010-2011 年的费用,应用 HRG4 代码和 2010-11-NHS 信托国家时间表对 2007-2008 年的数据进行了计算。

结果

在 5 年内,共记录了 75157 例掌腱膜挛缩症入院病例,其中 64506 例进行了分析。每年的平均入院人数为 12901 人,且保持稳定。日间手术的比例从 42%(2003-2004 年)增加到 62%(2007-2008 年)。每年有两次或以上入院的患者比例从 2003-2004 年的 5.5%增加到 2007-2008 年的 26.1%。2003 年至 2007 年期间,91%的手术是筋膜切开术。筋膜切开术和筋膜切除术的修订分别占约 4%;截肢占 1%。2007 年,分类方法扩展到包括数字筋膜切开术、其修订和真皮筋膜切开术。2007-2008 年的入院病例为:70%的掌腱膜切开术、16%的数字筋膜切开术、1.3%的其他筋膜切开术、4.4%的掌腱膜切开术修订、1.3%的数字筋膜切开术修订、3.8%的掌腱膜切开术、2.6%的真皮筋膜切开术和 1.1%的截肢术。79%的病例由创伤和矫形外科医生管理,19%由整形外科医生管理。2003-2004 年和 2007-2008 年的住院平均(±SD)住院时间分别为 1.5(±1.4)天和 1.0(±1.3)天。1 年(2010-2011)的总估计费用为 41576141 英镑。每位患者的费用为 2885 英镑(日间手术)和 3534 英镑(住院)。费用范围从 2736 英镑(日间手术筋膜切开术)到 9210 英镑(日间手术数字修订术)。

结论

2003 年至 2008 年间,在英格兰,筋膜切开术是治疗掌腱膜挛缩症最常见的手术方法。尽管手术率和医生专业略有不同,但手术场所发生了逆转:随着日间手术的增加,住院手术减少。这种变化可能是由于经济趋势和医疗保健系统的变化所致。2010-2011 年的估计费用因手术类型和患者状况而异。这些发现可用于了解掌腱膜挛缩症的临床治疗管理,并指导医疗保健政策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da69/3103491/7a2701ee7e49/1471-2474-12-73-1.jpg

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