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[因丝膜菌中毒导致的急性肾衰竭]

[Acute renal failure due to Cortinarius poisoning].

作者信息

Bouhbouh Souad, Haverkamp Leonie, Kuyper Thomas W, de Wolff Frederik A, Barendregt Jos N M

机构信息

Gelre Ziekenhuizen, afdeling Interne geneeskunde Apeldoorn, the Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2011;155:A3019.

Abstract

BACKGROUND

Ingestion of certain Cortinarius species may lead to renal failure. In the Netherlands, this type of poisoning has not been previously described.

CASUS

A 58-year-old female presented with headache, vomiting and oliguria, preceded by a few days of burning, painful thirst and malaise. She had acute and irreversible renal failure of unknown cause. History revealed that two days before the onset of her symptoms, she had eaten a ragout prepared with mushrooms that were picked in a forest. A renal biopsy demonstrated interstitial nephritis with proximal tubular necrosis. In the leftovers of the ragout two fragments of Cortinarius mushroom, probably belonging to the complex of Cortinarius cinnamomeus (cinnamon webcap), were found. First signs and symptoms, and the course are compatible with those described in the literature on Cortinarius poisoning. Despite haemodialysis and administration of acetylcysteine and glucocorticoids, her renal function did not recover.

CONCLUSION

This case is the first description of mushroom poisoning by a species of the genus Cortinarius in the Netherlands.

摘要

背景

摄入某些丝膜菌属物种可能导致肾衰竭。在荷兰,此前尚未有过此类中毒事件的描述。

病例

一名58岁女性出现头痛、呕吐和少尿症状,在此之前的几天里有灼痛、口渴和不适。她患有病因不明的急性不可逆肾衰竭。病史显示,在症状出现前两天,她食用了一道用在森林中采摘的蘑菇制作的炖菜。肾脏活检显示为间质性肾炎伴近端肾小管坏死。在炖菜的剩余物中发现了两块丝膜菌蘑菇碎片,可能属于肉桂丝膜菌(肉桂网帽菌)复合体。最初的症状和病程与丝膜菌中毒的文献描述相符。尽管进行了血液透析并给予了乙酰半胱氨酸和糖皮质激素,但她的肾功能并未恢复。

结论

该病例是荷兰首例关于丝膜菌属物种蘑菇中毒的描述。

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