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重症肌无力患者红细胞上补体C3b/C4b受体(CR1)的表达

Expression of complement C3b/C4b receptors (CR1) on erythrocytes from patients with myasthenia gravis.

作者信息

Vedeler C A, Gilhus N E, Matre R

机构信息

Department of Neurology, University of Bergen, Norway.

出版信息

Acta Neurol Scand. 1990 Oct;82(4):259-62. doi: 10.1111/j.1600-0404.1990.tb01616.x.

Abstract

The complement C3b/C4b receptor (CR1) expression on erythrocytes (E) (ECR1) from patients with myasthenia gravis (MG) and from blood donors was measured using haemadsorption and indirect hemagglutination techniques. The ECR1 expression in patients with MG appeared to be normal. This was also true for the subgroup of MG patients with additional autoimmune diseases. No correlation between ECR1 expression and severity of myasthenic symptoms was demonstrated.

摘要

采用血细胞吸附和间接血凝技术,检测了重症肌无力(MG)患者和献血者红细胞(E)上补体C3b/C4b受体(CR1)的表达(ECR1)。MG患者的ECR1表达似乎正常。合并其他自身免疫性疾病的MG患者亚组也是如此。未证实ECR1表达与肌无力症状严重程度之间存在相关性。

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