Matre R, Vedeler C A, Halvorsen O J
Immunol Lett. 1987 Apr;14(4):321-3. doi: 10.1016/0165-2478(87)90012-5.
The glomerular C3b receptor (CR1) activity was measured in cryostat sections of 100 normal kidneys obtained at autopsy using haemadsorption of erythrocytes (E) sensitized with rabbit IgM antibodies (A) and human complement (C) (EAC). The CR1 activity was classified as high, intermediate or low according to the degree of haemadsorption of EAC. High glomerular CR1 activity was found in 25% of the kidneys, intermediate activity in 62% and low activity in 12% of the kidneys. EAC did not adhere to glomeruli in 1% of the samples. The distribution of the glomerular CR1 activity is very similar to the phenotypic distribution of CR1 activity on erythrocytes from healthy individuals.
使用经兔IgM抗体（A）和人补体（C）致敏的红细胞（E）（EAC）的血细胞吸附法，对100例尸检获得的正常肾脏的冷冻切片中的肾小球C3b受体（CR1）活性进行了测定。根据EAC的血细胞吸附程度，将CR1活性分为高、中、低三类。在25%的肾脏中发现高肾小球CR1活性，62%为中等活性，12%为低活性。在1%的样本中，EAC未黏附于肾小球。肾小球CR1活性的分布与健康个体红细胞上CR1活性的表型分布非常相似。
