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犬蛋白丢失性肠病

Protein-losing enteropathies in dogs.

作者信息

Dossin Olivier, Lavoué Rachel

机构信息

Department of Clinical Sciences, National Veterinary School, 23 Chemin des Capelles, BP 87614, 31076 Toulouse cedex 3, France.

出版信息

Vet Clin North Am Small Anim Pract. 2011 Mar;41(2):399-418. doi: 10.1016/j.cvsm.2011.02.002.

Abstract

Protein-losing enteropathy is common in dogs but rare in cats. In the vast majority of cases, it is associated with inflammatory bowel disease, intestinal lymphoma, or intestinal lymphangiectasia. The diagnosis is based on identification of hypoalbuminemia and ruling out urinary loss and liver failure. Identification of the intestinal lesion with appropriate biopsy method is important to rule out neoplasm or infectious causes. The treatment is based on intensive nutritional support, therapy for the causative condition, and early monitoring of possibly life-threatening complications, such as hypocobalaminemia, massive pleural or abdominal fluid collection, thromboembolism, and hypocalcemia or hypomagnesemia.

摘要

蛋白丢失性肠病在犬中很常见,但在猫中很少见。在绝大多数情况下,它与炎症性肠病、肠道淋巴瘤或肠淋巴管扩张有关。诊断基于低白蛋白血症的识别,并排除尿液丢失和肝功能衰竭。采用适当的活检方法识别肠道病变对于排除肿瘤或感染性病因很重要。治疗基于强化营养支持、针对病因的治疗以及对可能危及生命的并发症(如低钴胺素血症、大量胸腔或腹腔积液、血栓栓塞以及低钙血症或低镁血症)的早期监测。

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