Lee Yujin, Choi Hojung, Lee Young-Won, Lee Kija, Choi Sooyoung
College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, South Korea.
College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
Vet Radiol Ultrasound. 2025 May;66(3):e70039. doi: 10.1111/vru.70039.
The intestinal vicarious contrast medium excretion (VCME) can occur in dogs with protein-losing enteropathy (PLE), and studies for intestinal VCME in dogs are lacking. This retrospective case-control study aimed to assess whether intestinal VCME could be observed on delayed CT in dogs with and without PLE. Thirty dogs who underwent abdominal delayed CT in the 10 min-delayed phase following the injection of contrast medium were enrolled. Six dogs were classified into the group with enteropathy based on imaging findings or abnormal results from cytology or histology. The six dogs had concurrent hypoalbuminemia and were diagnosed with presumed PLE. Five of the six dogs in the group with enteropathy had intestinal VCME. In the 24 dogs of the group without enteropathy, intestinal VCME was not detected on delayed CT, and VCME to the cisterna chyli was observed in one dog. The frequency of intestinal VCME was significantly higher in the group with enteropathy than in the group without enteropathy (p < .001). The presence of intestinal VCME on the delayed CT can be observed in dogs with PLE, and it can be used as noninvasive additional supportive evidence of canine PLE prior to histopathologic evaluation.
肠道替代性造影剂排泄（VCME）可发生于患有蛋白丢失性肠病（PLE）的犬只中，而关于犬只肠道VCME的研究尚缺。这项回顾性病例对照研究旨在评估在有或无PLE的犬只中，延迟CT上是否能观察到肠道VCME。纳入了30只在注射造影剂后10分钟延迟期接受腹部延迟CT检查的犬只。根据影像学表现或细胞学或组织学异常结果，6只犬被归类为患有肠病的组。这6只犬同时伴有低白蛋白血症，并被诊断为疑似PLE。患有肠病组的6只犬中有5只出现肠道VCME。在无肠病组的24只犬中，延迟CT上未检测到肠道VCME，仅在1只犬中观察到乳糜池的VCME。患有肠病组的肠道VCME发生率显著高于无肠病组（p <.001）。在患有PLE的犬只中，延迟CT上可观察到肠道VCME，并且在组织病理学评估之前，它可作为犬PLE的非侵入性额外支持证据。
