Faculdade Social da Bahia, Hospital Ana Nery, Salvador, BA, Brazil.
Arq Bras Cardiol. 2011 Mar;96(3):227-32. doi: 10.1590/s0066-782x2011005000002. Epub 2011 Jan 7.
Heart failure (HF) is an important public health problem, of which main clinical symptoms are dyspnea and fatigue. Noninvasive ventilatory support has been used as adjuvant therapy in cardiac rehabilitation in order to improve the functional capacity of patients.
To evaluate the functional capacity of patients with HF submitted to ventilatory support.
We evaluated the sociodemographic information, as well as data on quality of life, blood pressure (BP), peripheral oxygen saturation (SpO2), dyspnea, lactate concentration before and after the 6-minute walk test (6MWT) and the distance walked by patients of both sexes with chronic heart failure (CHF), with left ventricular ejection fraction (LVEF) < 45.0% , randomized in two groups: control and CPAP (the group used CPAP - 10 cmH2O for 30 minutes).
A total of 12 patients, of which 8 were males, with CHF functional class II and III (NYHA) participated in the study. The patients had mean LVEF of 35.3 ± 8.7 and mean age was 46.3 ± 10.3 years. When comparing the control group with the CPAP group at the end of the 6th minute, there was a significant difference between the groups regarding SpO2 values (
93.6 ± 1.5 % vs CPAP: 96.1±1.8%; p = 0.027), index of dyspnea (
13.1 ± 1.16 vs CPAP: 11 ± 0.8; p = 0.009), lactate concentration (
3.3 ± 0.7 mmol/l vs CPAP: 2.3 ± 0.5 mmol/l; p = 0.025) and distance walked at the 6MWT (CONTROL: 420.6 ± 73.8 m vs CPAP: 534 ± 89.91 m; p = 0.038).
The previous use of the CPAP had beneficial effects on SpO2, index of dyspnea, lactate concentration, double product and the distance walked at the 6MWT in patients with CHF when performing the 6MWT.
心力衰竭（HF）是一个重要的公共卫生问题，其主要临床症状是呼吸困难和疲劳。无创通气支持已被用作心脏康复的辅助治疗，以提高患者的功能能力。
评估接受通气支持的心力衰竭患者的功能能力。
我们评估了社会人口统计学信息，以及生活质量、血压（BP）、外周血氧饱和度（SpO2）、呼吸困难、6 分钟步行试验（6MWT）前后乳酸浓度以及左心室射血分数（LVEF）<45.0%的慢性心力衰竭（CHF）患者的性别、距离，将患者随机分为两组：对照组和 CPAP 组（CPAP 组使用 10 cmH2O 持续 30 分钟）。
共有 12 名患者，其中 8 名男性，NYHA 心功能 II 级和 III 级（NYHA），参与了这项研究。患者的平均 LVEF 为 35.3 ± 8.7，平均年龄为 46.3 ± 10.3 岁。在第 6 分钟末比较对照组和 CPAP 组时，两组 SpO2 值（
93.6 ± 1.5%vs CPAP 组：96.1±1.8%；p = 0.027）、呼吸困难指数（
13.1 ± 1.16 vs CPAP 组：11 ± 0.8；p = 0.009）、乳酸浓度（
3.3 ± 0.7 mmol/L vs CPAP 组：2.3 ± 0.5 mmol/L；p = 0.025）和 6MWT 行走距离（
420.6 ± 73.8 m vs CPAP 组：534 ± 89.91 m；p = 0.038）有显著差异。
在进行 6MWT 时，CHF 患者使用 CPAP 前有有益的效果，表现在 SpO2、呼吸困难指数、乳酸浓度、双乘积和 6MWT 行走距离上。
