Bündchen Daiana C, Gonzáles Ana I, Noronha Marcos De, Brüggemann Ana K, Sties Sabrina W, Carvalho Tales De
Centro de Ciências da Saúde e do Esporte, Universidade do Estado de Santa Catarina, Florianópolis, SC, Brazil.
Braz J Phys Ther. 2014 Sep-Oct;18(5):385-94. doi: 10.1590/bjpt-rbf.2014.0039. Epub 2014 Sep 12.
Patients with heart failure (HF) usually develop exercise intolerance. In this context, noninvasive ventilation (NIV) can help to increase physical performance.
To undertake a systematic review and meta-analysis of randomized controlled trials that evaluated the effects of NIV on exercise tolerance in patients with HF.
Search Strategy: Articles were searched in the following databases: Physiotherapy Evidence Database (PEDro), Scientific Electronic Library Online (SciELO), and MEDLINE. Selection Criteria: This review included only randomized controlled trials involving patients with HF undergoing NIV, with or without other therapies, that used exercise tolerance as an outcome, verified by the distance travelled in the six-minute walk test (6MWT), VO2peak in the cardiopulmonary test, time spent in testing, and dyspnea. Data Collection And Analysis: The methodological quality of the studies was rated according to the PEDro scale. Data were pooled in fixed-effect meta-analysis whenever possible.
Four studies were selected. A meta-analysis including 18 participants showed that the use of NIV prior to the 6MWT promoted increased distance, [mean difference 65.29 m (95% CI 38.80 to 91.78)].
The use of NIV prior to the 6MWT in patients with HF may promote increased distance. However, the limited number of studies may have compromised a more definitive conclusion on the subject.
心力衰竭（HF）患者通常会出现运动不耐受。在此背景下，无创通气（NIV）有助于提高身体机能。
对评估NIV对HF患者运动耐量影响的随机对照试验进行系统评价和荟萃分析。
检索策略：在以下数据库中检索文章：物理治疗证据数据库（PEDro）、科学电子图书馆在线（SciELO）和医学文献数据库（MEDLINE）。选择标准：本评价仅纳入涉及接受NIV治疗的HF患者的随机对照试验，无论是否接受其他治疗，以运动耐量作为结局指标，通过六分钟步行试验（6MWT）中的行走距离、心肺试验中的峰值摄氧量、测试时间和呼吸困难进行验证。数据收集与分析：根据PEDro量表对研究的方法学质量进行评分。尽可能采用固定效应荟萃分析合并数据。
选择了四项研究。一项纳入18名参与者的荟萃分析表明，在6MWT之前使用NIV可增加行走距离，[平均差值65.29米（95%置信区间38.80至91.78）]。
HF患者在6MWT之前使用NIV可能会增加行走距离。然而，研究数量有限可能影响了对该主题得出更明确的结论。
