Malaia L T, Volnenko N B, Gorb Iu G
Kardiologiia. 1990 Sep;30(9):28-30.
Alpha-atrial natriuretic peptide (ANP) levels, plasma renin activity, and plasma aldosterone levels were measured in 103 patients with coronary heart disease (CHD) having signs of various circulatory failures. The parameters were studied in relation to central hemodynamic values, and their dependence on the stage of chronic circulatory failure. Alpha-ANP was found to be one of the factors of the humoral systems implicated in the pathogenesis of chronic circulatory failure in CHD patients. The plasma level of alpha-ANP was found to be related to the state of the renin-angiotensin-aldosterone system both in healthy subjects and CHD patients.
对103例有各种循环衰竭体征的冠心病（CHD）患者测定了α-心房利钠肽（ANP）水平、血浆肾素活性和血浆醛固酮水平。研究了这些参数与中心血流动力学值的关系，以及它们对慢性循环衰竭阶段的依赖性。发现α-ANP是参与冠心病患者慢性循环衰竭发病机制的体液系统因素之一。发现在健康受试者和冠心病患者中，α-ANP的血浆水平均与肾素-血管紧张素-醛固酮系统的状态有关。
