Ertel S I, Ratner B D, Horbett T A
Department of Chemical Engineering, University of Washington, Seattle 98195.
J Biomed Mater Res. 1990 Dec;24(12):1637-59. doi: 10.1002/jbm.820241207.
Polystyrene and poly(ethylene terephthalate) substrates were modified by radiofrequency plasma deposition with organic vapors comprised of carbon, oxygen, and hydrogen (acetone, methanol, glutaraldehyde, formic acid, allyl alcohol, and ethylene oxide). The treatments resulted in the deposition of a film at least 100 A thick containing up to 26% atomic oxygen at the surface. A high oxygen incorporation was observed for vapors with a large oxygen-to-carbon ratio. Bovine aortic endothelial cell growth measured on acetone, methanol, and glutaraldehyde films was linearly correlated with the oxygen content of the treated surfaces. Nitrogen was incorporated in the surface by blending nitrogen gas into the organic vapor used for plasma deposition. The resulting nitrogen-containing substrates exhibited a high affinity for serum fibronectin but a moderate cell growth.
通过射频等离子体沉积，用由碳、氧和氢组成的有机蒸汽（丙酮、甲醇、戊二醛、甲酸、烯丙醇和环氧乙烷）对聚苯乙烯和聚对苯二甲酸乙二酯基材进行改性。这些处理导致在表面沉积了至少100埃厚的薄膜，其表面含氧量高达26%原子。对于氧碳比大的蒸汽，观察到有高的氧掺入量。在丙酮、甲醇和戊二醛薄膜上测量的牛主动脉内皮细胞生长与处理过的表面的氧含量呈线性相关。通过将氮气混入用于等离子体沉积的有机蒸汽中，使氮掺入表面。所得含氮基材对血清纤连蛋白具有高亲和力，但细胞生长适中。
