Canady J W, Squier C A, Kelly K M, Bardach J
Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City 52242.
Otolaryngol Head Neck Surg. 1990 Dec;103(6):986-90. doi: 10.1177/019459989010300617.
This study provides additional information about changes in blood flow in expanded tissue as measured by laser Doppler. Five one-kilogram albino Hartley guinea pigs were implanted with commercially available hemispheric expanders. The expanders were inflated every 3 days on four successive occasions. Blood flow measurements were taken on each animal just before each inflation, immediately after inflation, and then at 1, 2, 3, 4, and 24 hours after expansion. Measurement of flow changes immediately after each inflation of the expander showed that, initially, blood flow in the tissue overlying the expander recovered quickly, but as the expansion process was continued, the flow did not return to baseline values so rapidly. This might be an indication that tissue expansion in patients could be carried out more rapidly during the initial inflations, with increasing recovery periods between inflations as the expansion process continued.
本研究提供了关于通过激光多普勒测量的扩张组织中血流变化的更多信息。五只一千克重的白化病哈特利豚鼠植入了市售的半球形扩张器。扩张器在连续四次的情况下每三天充气一次。在每次充气前、充气后立即以及扩张后1、2、3、4和24小时对每只动物进行血流测量。对扩张器每次充气后立即进行的血流变化测量表明，最初，扩张器上方组织中的血流迅速恢复，但随着扩张过程的持续，血流并未如此迅速地恢复到基线值。这可能表明，在初始充气期间，患者的组织扩张可以更快地进行，随着扩张过程的持续，充气之间的恢复时间会增加。
