Timmenga E J, Schoorl R, Bos J D, Klopper P J
University of Amsterdam, Academic Medical Centre, The Netherlands.
Br J Plast Surg. 1989 May;42(3):301-5. doi: 10.1016/0007-1226(89)90151-3.
A pocket for tissue expander implantation in the rabbit is described at the level between the skin and the panniculus carnosus. The vascular anatomy of the undermined skin was studied with microangiography which showed a functional (sub)dermal plexus. Expanders were placed in seven rabbits and inflated daily over a period of 10 days. Blood flow in expanded skin, as measured with laser Doppler flowmetry, dropped with increasing inflation pressure. During the course of expansion, the intraluminal pressure returned to a baseline level within 24 hours after each inflation. It is concluded that an expander placed in the described layer in the rabbit causes considerable skin stretch and interferes with cutaneous blood supply and is therefore an improved model for tissue expansion in the human.
本文描述了在兔的皮肤和肉膜之间的层面植入组织扩张器的一个腔隙。通过微血管造影术研究了潜行分离皮肤的血管解剖结构，结果显示存在一个功能性的（皮下）真皮血管丛。在7只兔中植入扩张器，并在10天内每日进行充气。用激光多普勒血流仪测量发现，随着充气压力增加，扩张皮肤中的血流下降。在扩张过程中，每次充气后24小时内管腔内压力恢复到基线水平。结论是，置于兔上述层面的扩张器可引起显著的皮肤拉伸并干扰皮肤血液供应，因此是人类组织扩张的一种改进模型。
