Functional Genomics and Plant Molecular Imaging, Center for Protein Engineering, Department of Life Sciences (B22), University of Liège, Belgium.
Trends Plant Sci. 2011 Jul;16(7):395-404. doi: 10.1016/j.tplants.2011.03.005. Epub 2011 Apr 12.
Transition metal deficiency has a strong impact on the growth and survival of an organism. Indeed, transition metals, such as iron, copper, manganese and zinc, constitute essential cofactors for many key cellular functions. Both photosynthesis and respiration rely on metal cofactor-mediated electron transport chains. Chloroplasts and mitochondria are, therefore, organelles with high metal ion demand and represent essential components of the metal homeostasis network in photosynthetic cells. In this review, we describe the metal requirements of chloroplasts and mitochondria, the acclimation of their functions to metal deficiency and recent advances in our understanding of their contributions to cellular metal homeostasis, the control of the cellular redox status and the synthesis of metal cofactors.
过渡金属缺乏对生物体的生长和存活有强烈的影响。实际上，过渡金属如铁、铜、锰和锌，是许多关键细胞功能的必需辅助因子。光合作用和呼吸作用都依赖于金属辅助因子介导的电子传递链。因此，叶绿体和线粒体是对金属离子有高需求的细胞器，也是光合细胞中金属稳态网络的重要组成部分。在这篇综述中，我们描述了叶绿体和线粒体的金属需求、它们的功能对金属缺乏的适应，以及我们对它们在细胞金属稳态、细胞氧化还原状态的控制和金属辅助因子合成中的贡献的最新理解。
