College of Veterinary Medicine, Konkuk University, Gwangjin-gu, Seoul, Republic of Korea.
Poult Sci. 2011 May;90(5):1020-2. doi: 10.3382/ps.2010-01258.
The frequent economic losses incurred with H9N2 low pathogenic avian influenza viruses (LPAI) infection have raised serious concerns for the poultry industry. A 1-dose regimen with inactivated H9N2 LPAI vaccine could not prevent vaccinated poultry from becoming infected and from shedding wild viruses. A study was conducted to determine whether a 2-dose regimen of inactivated H9N2 LPAI vaccine could enhance the immunologic response in chickens. Such gel-primed and mineral oil-boosted regimen has produced encouraging results associated with improved immune responses to an H9N2 LPAI. This strategy could be cost effective and helpful for preventing avian influenza virus in the poultry industry.
H9N2 低致病性禽流感病毒（LPAI）感染造成的频繁经济损失引起了家禽业的严重关注。使用 1 剂灭活 H9N2 LPAI 疫苗的方案无法预防接种家禽感染和传播野生病毒。本研究旨在确定 2 剂灭活 H9N2 LPAI 疫苗是否可以增强鸡的免疫反应。这种凝胶引发和矿物油增强的方案已经产生了令人鼓舞的结果，与改善对 H9N2 LPAI 的免疫反应有关。这种策略具有成本效益，可以帮助家禽业预防禽流感病毒。
