Privalenko S V, Badokin V V
Vestn Dermatol Venerol. 1990(10):11-7.
Blood and serum glucosaminoglycanes, serum glycosaminoglycane hydrolases, hydroxyprolinuria were measured in 140 patients, 60 of these suffering from psoriasis and 80 from psoriatic arthropathy. A relationship between the severity of impairments of connective tissue metabolism and dissemination of the skin process, as well as activity of articular and visceral inflammations, was examined. The detected regularities are discussed in the light of psoriasis pathogenesis; differential diagnostic potentialities of these regularities are analyzed.
对140例患者进行了血液和血清葡糖胺聚糖、血清葡糖胺聚糖水解酶、羟脯氨酸尿的检测,其中60例患有银屑病,80例患有银屑病关节炎。研究了结缔组织代谢损害的严重程度与皮肤病变播散以及关节和内脏炎症活动之间的关系。根据银屑病的发病机制对检测到的规律进行了讨论;分析了这些规律的鉴别诊断潜力。