Guo Yi, Kim Eun H, Alvarez Tara L
Department of Biomedical Engineering, New Jersey Institute of Technology, USA.
J Vis Exp. 2011 Mar 25(49):2530. doi: 10.3791/2530.
Eye movement studies have provided a strong foundation forming an understanding of how the brain acquires visual information in both the normal and dysfunctional brain.(1) However, development of a platform to stimulate and store eye movements can require substantial programming, time and costs. Many systems do not offer the flexibility to program numerous stimuli for a variety of experimental needs. However, the VisualEyes System has a flexible architecture, allowing the operator to choose any background and foreground stimulus, program one or two screens for tandem or opposing eye movements and stimulate the left and right eye independently. This system can significantly reduce the programming development time needed to conduct an oculomotor study. The VisualEyes System will be discussed in three parts: 1) the oculomotor recording device to acquire eye movement responses, 2) the VisualEyes software written in LabView, to generate an array of stimuli and store responses as text files and 3) offline data analysis. Eye movements can be recorded by several types of instrumentation such as: a limbus tracking system, a sclera search coil, or a video image system. Typical eye movement stimuli such as saccadic steps, vergent ramps and vergent steps with the corresponding responses will be shown. In this video report, we demonstrate the flexibility of a system to create numerous visual stimuli and record eye movements that can be utilized by basic scientists and clinicians to study healthy as well as clinical populations.
眼动研究为理解大脑在正常和功能失调状态下如何获取视觉信息奠定了坚实基础。(1)然而,开发一个用于刺激和存储眼动的平台可能需要大量的编程工作、时间和成本。许多系统缺乏灵活性,无法针对各种实验需求编写大量刺激程序。然而,VisualEyes系统具有灵活的架构,允许操作人员选择任何背景和前景刺激,为串联或反向眼动编写一个或两个屏幕的程序,并独立刺激左眼和右眼。该系统可以显著减少进行动眼神经研究所需的编程开发时间。VisualEyes系统将分三个部分进行讨论:1)用于获取眼动反应的动眼神经记录设备;2)用LabView编写的VisualEyes软件,用于生成一系列刺激并将反应存储为文本文件;3)离线数据分析。眼动可以通过几种仪器进行记录,如:角膜缘跟踪系统、巩膜搜索线圈或视频图像系统。将展示典型的眼动刺激,如扫视步阶、聚散斜坡和聚散步阶以及相应的反应。在本视频报告中,我们展示了一个系统创建大量视觉刺激并记录眼动的灵活性,基础科学家和临床医生可以利用这些来研究健康人群以及临床患者群体。