Bernardini A, Larrabide I, Petrini L, Pennati G, Flore E, Kim M, Frangi A F
Center for Computational Imaging and Simulation Technologies in Biomedicine (CISTIB), Universitat Pompeu Fabra (UPF), C/Roc Boronat 138, 08018 Barcelona, Spain.
Comput Methods Biomech Biomed Engin. 2012;15(3):303-11. doi: 10.1080/10255842.2010.527838. Epub 2011 Jun 1.
In the last few years, there has been a growing focus on faster computational methods to support clinicians in planning stenting procedures. This study investigates the possibility of introducing computational approximations in modelling stent deployment in aneurysmatic cerebral vessels to achieve simulations compatible with the constraints of real clinical workflows. The release of a self-expandable stent in a simplified aneurysmatic vessel was modelled in four different initial positions. Six progressively simplified modelling approaches (based on Finite Element method and Fast Virtual Stenting--FVS) have been used. Comparing accuracy of the results, the final configuration of the stent is more affected by neglecting mechanical properties of materials (FVS) than by adopting 1D instead of 3D stent models. Nevertheless, the differences showed are acceptable compared to those achieved by considering different stent initial positions. Regarding computational costs, simulations involving 1D stent features are the only ones feasible in clinical context.
在过去几年中,人们越来越关注更快的计算方法,以支持临床医生进行支架置入手术的规划。本研究探讨了在模拟动脉瘤性脑血管中的支架展开时引入计算近似方法的可能性,以实现与实际临床工作流程的约束条件相兼容的模拟。在四个不同的初始位置对简化的动脉瘤性血管中自膨胀支架的释放进行了建模。使用了六种逐步简化的建模方法(基于有限元法和快速虚拟支架——FVS)。比较结果的准确性,与采用1D而非3D支架模型相比,忽略材料的力学性能(FVS)对支架的最终构型影响更大。然而,与考虑不同支架初始位置所获得的差异相比,所显示的差异是可以接受的。关于计算成本,涉及1D支架特征的模拟是临床环境中唯一可行的模拟。