Nemoto O, Moser R P, Van Dam B E, Aoki J, Gilkey F W
Department of Orthopaedics, Walter Reed Army Medical Center, Washington, District of Columbia.
Spine (Phila Pa 1976). 1990 Dec;15(12):1272-80. doi: 10.1097/00007632-199012000-00008.
Clinical and radiologic features of 75 cases of osteoblastoma of the spine were reviewed. In addition to pain, which was the most frequent complaint, 18 patients demonstrated objective neurologic deficit, while scoliosis was observed in 17 patients. Aspirin yielded pain relief in 13 patients. Pathologic fracture was not encountered. The radiologic and histologic characteristics of osteoblastoma of the spine are indistinguishable from those arising in other sites. The typical lesion exhibited a well-defined, geographic margin with a sclerotic, frequently lobulated border. Approximately one half of the cases were predominantly lucent, the remainder displaying varying degrees of matrix mineralization. Distribution of the osteoblastomas through the spinal axis was as follows: cervical-29, thoracic-16, lumbar-17, sacral-13. Other significant findings included posterior element involvement in 73 of 75 cases, and a striking male to female ratio of 2.5 to 1.
回顾了75例脊柱骨母细胞瘤的临床和放射学特征。除了疼痛（最常见的主诉）外，18例患者出现客观神经功能缺损，17例患者观察到脊柱侧凸。阿司匹林使13例患者疼痛缓解。未发生病理性骨折。脊柱骨母细胞瘤的放射学和组织学特征与其他部位发生的骨母细胞瘤无异。典型病变表现为边界清晰、呈地图样，边界硬化，常呈分叶状。约一半病例主要为透亮区，其余病例显示不同程度的基质矿化。骨母细胞瘤在脊柱轴线上的分布如下：颈椎29例，胸椎16例，腰椎17例，骶骨13例。其他重要发现包括75例中的73例累及后部结构，男女比例显著为2.5比1。
