• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

精原细胞瘤治疗后出现弛缓性神经性膀胱的放射性腰骶神经根病:一例报告

Postirradiation lumbosacral radiculopathy following seminoma treatment presenting as flaccid neuropathic bladder: a case report.

作者信息

Raheem Omer A, Hickey David P

机构信息

Department of Urology and Transplantation, Beaumont Hospital, Dublin, Ireland.

出版信息

J Med Case Rep. 2011 Apr 14;5:148. doi: 10.1186/1752-1947-5-148.

DOI:10.1186/1752-1947-5-148
PMID:21492468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3094292/
Abstract

INTRODUCTION

Postirradiation lumbosacral syndrome is a radiculopathy induced by radiation injury to the spinal cord. Its usual presentation is motor deficit and or sensory loss involving the lower limbs. Visceral involvement has not been reported previously.

CASE PRESENTATION

We describe a case of severe hypotonic bladder caused by radiation-induced spinal cord injury following treatment of stage Ι testicular seminoma in a 38-year-old Caucasian man who had undergone radical orchidectomy and prophylactic paraaortic lymph node irradiation for stage Ι seminoma. Three years later he had clinical and urodynamic findings of hypotonic bladder. The magnetic resonance imaging results suggested a radiation-induced injury.

CONCLUSION

Such an unusual presentation of the syndrome of postirradiation lumbosacral radiculopathy can impose a clinical challenge to practicing clinicians. Future studies are required to further delineate the mechanism of injury and further management plans.

摘要

引言

放射后腰骶综合征是一种因脊髓辐射损伤所致的神经根病。其常见表现为下肢运动功能障碍和/或感觉丧失。此前尚未有内脏受累的报道。

病例报告

我们描述了一例38岁白人男性,在接受根治性睾丸切除及针对Ⅰ期精原细胞瘤的预防性腹主动脉旁淋巴结照射后,因放射性脊髓损伤导致严重张力性膀胱的病例。三年后,他出现了张力性膀胱的临床及尿动力学表现。磁共振成像结果提示为放射性损伤。

结论

放射后腰骶神经根病综合征的这种不寻常表现会给临床医生带来临床挑战。需要进一步研究以明确损伤机制及进一步的治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51c6/3094292/3d955d092647/1752-1947-5-148-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51c6/3094292/3d955d092647/1752-1947-5-148-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51c6/3094292/3d955d092647/1752-1947-5-148-1.jpg

相似文献

1
Postirradiation lumbosacral radiculopathy following seminoma treatment presenting as flaccid neuropathic bladder: a case report.精原细胞瘤治疗后出现弛缓性神经性膀胱的放射性腰骶神经根病:一例报告
J Med Case Rep. 2011 Apr 14;5:148. doi: 10.1186/1752-1947-5-148.
2
Inguinal lymph node metastases from a testicular seminoma: a case report and a review of the literature.睾丸精原细胞瘤腹股沟淋巴结转移:一例报告并文献复习
J Med Case Rep. 2010 Nov 25;4:378. doi: 10.1186/1752-1947-4-378.
3
[A case of post-irradiation lumbosacral radiculopathy successfully treated with corticosteroid and warfarin].[一例采用皮质类固醇和华法林成功治疗的放疗后腰骶神经根病]
Rinsho Shinkeigaku. 1999 Aug;39(8):825-9.
4
Postradiation lumbosacral radiculopathy with spinal root cavernomas mimicking carcinomatous meningitis.放射性腰骶神经根病合并脊髓神经根海绵状血管瘤,酷似癌性脑膜炎。
Neuro Oncol. 2008 Dec;10(6):1035-9. doi: 10.1215/15228517-2008-069. Epub 2008 Aug 28.
5
Malignant spinal cord compression secondary to testicular seminoma at the time of initial presentation and at relapse while on surveillance.初次就诊时以及在监测期间复发时,睾丸精原细胞瘤继发恶性脊髓压迫。
Can Urol Assoc J. 2007 Mar;1(1):59-63. doi: 10.5489/cuaj.41.
6
Long term results and morbidity of paraaortic compared with paraaortic and iliac adjuvant radiation in clinical stage I seminoma.临床I期精原细胞瘤中,腹主动脉旁辅助放疗与腹主动脉旁及髂血管辅助放疗的长期结果及发病率比较
Anticancer Res. 2001 Jul-Aug;21(4B):2989-93.
7
[Lumbosacral radiculoplexus neuropathy with a small intramedullary lesion in posterior spinal cord: a case report].[腰骶神经根丛神经病合并脊髓后索小髓内病变:1例报告]
Rinsho Shinkeigaku. 2018 Dec 21;58(12):745-749. doi: 10.5692/clinicalneurol.cn-001213. Epub 2018 Nov 29.
8
Brain and spinal cord metastases with seminoma: A case report.精原细胞瘤脑和脊髓转移:一例报告。
IJU Case Rep. 2022 Aug 30;5(6):464-468. doi: 10.1002/iju5.12515. eCollection 2022 Nov.
9
Testicular seminoma--unusual histology and staging with sub epithelial spread of seminoma along the vas deferans.睾丸精原细胞瘤——不寻常的组织学表现及分期,精原细胞瘤沿输精管进行上皮下播散。
BMC Urol. 2006 Mar 1;6:5. doi: 10.1186/1471-2490-6-5.
10
[Long-term tumor control and fertility after para-aortic limited radiotherapy of stage I seminoma].
Strahlenther Onkol. 1999 Jul;175(7):320-4. doi: 10.1007/s000660050018.

引用本文的文献

1
Bilateral synchronous spermatocytic seminoma: a rare case report.双侧同步精母细胞性精原细胞瘤:一例罕见病例报告
Pan Afr Med J. 2014 Apr 14;17:275. doi: 10.11604/pamj.2014.17.275.4129. eCollection 2014.

本文引用的文献

1
Germ cell tumours of the testis.睾丸生殖细胞肿瘤
Crit Rev Oncol Hematol. 2005 Feb;53(2):141-64. doi: 10.1016/j.critrevonc.2004.05.006.
2
Pathology of radiation myelopathy.放射性脊髓病的病理学
Neuropathology. 2001 Dec;21(4):247-65. doi: 10.1046/j.1440-1789.2001.00408.x.
3
L4-5 disk lesion resulting in back pain with bowel, bladder and sexual dysfunction without paraparesis.
Spinal Cord. 1999 Mar;37(3):228-30. doi: 10.1038/sj.sc.3100760.
4
[Radiogenic amyotrophy. Cauda equina lesion as a late radiation sequela].
Nervenarzt. 1998 Dec;69(12):1061-5. doi: 10.1007/s001150050383.
5
The post-irradiation lower motor neuron syndrome neuronopathy or radiculopathy?
Brain. 1996 Oct;119 ( Pt 5):1429-39. doi: 10.1093/brain/119.5.1429.
6
Postradiation lower motor neuron syndrome presenting as monomelic amyotrophy.表现为单肢肌萎缩的放疗后下运动神经元综合征
J Neurol Neurosurg Psychiatry. 1991 Jul;54(7):648-9. doi: 10.1136/jnnp.54.7.648.