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面部皮肤下组织炎揭示了托法替尼诱导的狼疮样疾病(TIBOLA)

[Dermohypodermitis on the face revealing TIBOLA].

作者信息

Gaston J, Durox H, Sparsa A, Bonnetblanc J-M, Doffoel-Hantz V

机构信息

Service de dermatologie et vénéréologie, CHU Dupuytren, 2, avenue Martin Luther King, 87042 Limoges cedex, France.

Service de maladies infectieuses et tropicales, CHU de Limoges, 87042 Limoges cedex, France.

出版信息

Arch Pediatr. 2011 May;18(5):565-7. doi: 10.1016/j.arcped.2011.02.018. Epub 2011 Apr 13.

Abstract

Tick-borne lymphadenopathy (TIBOLA) is an emerging rickettsiosis in Europe, transmitted by the Dermacentor tick. This syndrome is defined as the association of an inoculation eschar on the scalp that may be surrounded by an erythema scalp, fever, and painful cervical lymphadenopathy in colder months. Children and women are at higher risk for TIBOLA. We report the case of a 9 year-old French child with an acute hemifacial edema and erythema revealing TIBOLA. Early empirical antibiotic therapy should be prescribed in any suspected TIBOLA, before confirmation of the diagnosis. The recommended treatment is doxycycline or macrolide.

摘要

蜱传淋巴结病(TIBOLA)是欧洲一种新出现的立克次体病,由革蜱传播。该综合征定义为在较寒冷月份头皮上出现接种性焦痂,焦痂周围可能有头皮红斑、发热及颈部疼痛性淋巴结病。儿童和女性患TIBOLA的风险更高。我们报告一例9岁法国儿童,以急性半侧面部水肿和红斑为表现,提示患有TIBOLA。在确诊之前,对于任何疑似TIBOLA的病例均应尽早给予经验性抗生素治疗。推荐的治疗药物是多西环素或大环内酯类药物。

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