Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency - Weybridge, Woodham Lane, Addlestone, Surrey KT15 3NB.
Vet Rec. 2011 Feb 5;168(5):128. doi: 10.1136/vr.c6364. Epub 2011 Jan 26.
During an outbreak of foot-and-mouth disease (FMD) in southern England in 2007, a case-control study was conducted to identify risk factors for infection and to investigate the relative impact of risk factors on transmission between the infected farms. Seven of the eight case farms in the outbreak and 22 control farms participated. Data were collected via questionnaires and subjected to comparative statistical analysis. Case farms were further classified as primary or secondary according to the likely source of infection during the study. On primary case farms, it was plausible that infection had been introduced directly from the original source. On secondary case farms, FMD infection was more likely to have originated from another infected premises. Calving occurred more frequently on case farms than on control farms during the risk period, and the two primary case farms had a larger proportion of youngstock than the other farms. Secondary case farms (n=5) had a higher composite environmental risk score and a lower biosecurity score than control farms.
2007 年，在英格兰南部爆发的口蹄疫疫情期间，开展了一项病例对照研究，以确定感染的风险因素，并调查这些风险因素对感染农场之间传播的相对影响。疫情中的 8 个病例农场中的 7 个和 22 个对照农场参与了该研究。通过问卷调查收集数据，并进行了对比统计分析。根据研究期间感染的可能来源，将病例农场进一步分为原发性或继发性。在原发性病例农场，感染很可能是直接从原始来源引入的。在继发性病例农场，口蹄疫感染更可能源自另一个感染场所。在风险期，病例农场的产犊频率高于对照农场，且两个原发性病例农场的幼畜比例高于其他农场。继发性病例农场（n=5）的综合环境风险评分较高，生物安全评分较低。
