Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California 94143-0100, USA.
Transfusion. 2011 Apr;51(4):737-41. doi: 10.1111/j.1537-2995.2010.02918.x. Epub 2010 Oct 26.
New criteria for young blood donors were recently developed to minimize faint reactions in this high-risk group. The aim of this study was to determine the impact implementation of these criteria would have on collections and donor faint or prefaint reaction rates at our university blood center.
Donor history questionnaires from eight consecutive undergraduate campus blood drives were retrospectively reviewed. Height, weight, sex, and age were used to determine the number of donors potentially deferred.
During the study period, 81% of donors were age 22 or younger (537/662) with a reaction rate of 2.4% (16/662). If these new height and weight criteria were implemented, 11.5% of our young donors would have been deferred (76/662) preventing 2 of 16 reactions. Revision of height and weight criteria with consideration for a 475-mL collection volume would decrease deferral rates to 1.2% (8/662) with no reactions prevented.
Implementation of new height and weight criteria based on a standard 525-mL collection volume would result in a high rate of donor deferral. Revised criteria adjusted for our smaller collection volume would significantly decrease donor deferral rates. All reactions observed in young donors during our study period occurred in those predicted to have a less than 15% decrease in total blood volume after donation.
最近制定了新的年轻献血者标准，以最大限度地减少这个高风险群体的晕厥反应。本研究旨在确定在我们的大学血液中心实施这些标准对采集和献血者晕厥或晕厥前反应率的影响。
回顾了连续 8 次本科校园献血活动的献血者病史问卷。身高、体重、性别和年龄用于确定可能被推迟的献血者人数。
在研究期间，81%的献血者年龄在 22 岁或以下（537/662），反应率为 2.4%（16/662）。如果实施这些新的身高和体重标准，我们的年轻献血者中有 11.5%（76/662）将被推迟，从而避免了 16 次反应中的 2 次。考虑到采集量为 475 毫升，修订身高和体重标准将使推迟率降至 1.2%（8/662），并且不会预防任何反应。
根据标准的 525 毫升采集量实施新的身高和体重标准，将导致献血者大量推迟献血。根据我们较小的采集量调整的标准将显著降低献血者的推迟率。我们研究期间观察到的所有年轻献血者的反应都发生在那些预测在献血后总血容量减少不到 15%的献血者中。
