Department of Pediatrics, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, 416 85 Gothenburg, Sweden.
Department of Pediatric Surgery, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, 416 85 Gothenburg, Sweden.
J Pediatr Surg. 2011 Apr;46(4):655-661. doi: 10.1016/j.jpedsurg.2010.10.028.
The aim was to investigate whether young children with drug-refractory nausea and vomiting can be treated with gastric electrical stimulation (GES) in a similar way as adults and to evaluate whether temporary percutaneous gastric electrical stimulation (TPGES) can be used in the pediatric population to select the patients who are responders to GES treatment. We report the clinical results in 3 children between 2 and 3 years of age. To the best of our knowledge, these are the youngest patients treated with GES.
Three patients younger than 3 years with intractable vomiting underwent TPGES. Custom-made leads were percutaneously implanted in the gastric wall under gastroscopic guidance. Symptoms were recorded daily during the TPGES stimulation time (12-40 days). Responders were offered permanent GES treatment.
There were no technical problems. All 3 patients were responders to TPGES. They are now treated with surgically implanted permanent GES and reported greater than 50% vomiting reduction at last visit.
Children younger than 3 years can be treated with GES in a similar way as adolescents and adults. Temporary percutaneous GES is a safe, feasible technique even in small children, with the possibility to perform the test over several weeks to select responders to GES treatment.
本研究旨在探讨药物难治性恶心和呕吐的幼儿是否可以像成人一样接受胃电刺激（GES）治疗，并评估经皮临时胃电刺激（TPGES）是否可用于儿科人群，以选择对 GES 治疗有反应的患者。我们报告了 3 名年龄在 2 至 3 岁之间的儿童的临床结果。据我们所知，这些是接受 GES 治疗的最小年龄的患者。
3 名年龄小于 3 岁的难治性呕吐患儿接受了 TPGES 治疗。在胃镜引导下经皮将定制的引线植入胃壁。在 TPGES 刺激期间（12-40 天）每天记录症状。对有反应的患者提供永久性 GES 治疗。
无技术问题。所有 3 名患儿对 TPGES 均有反应。他们现在接受手术植入的永久性 GES 治疗，在最近一次就诊时报告呕吐减少 50%以上。
小于 3 岁的儿童可以像青少年和成人一样接受 GES 治疗。临时经皮 GES 是一种安全、可行的技术，即使在幼儿中也是如此，它可以在数周内进行测试，以选择对 GES 治疗有反应的患者。
