Department of Stomatology, University of Barcelona, Catalonia, Spain.
J Endod. 2011 May;37(5):598-601. doi: 10.1016/j.joen.2011.01.002. Epub 2011 Mar 2.
The aim of this study was to investigate radiographically the prevalence of apical periodontitis (AP) and endodontic treatment in a sample of adult type II diabetic patients and control subjects.
In a cross-sectional study, the radiographic records of 50 adult patients reporting a history of well-controlled type 2 diabetes mellitus (DM) (study group) and 50 age- and sex-matched subjects who reported no history of DM (control group) were examined. Periapical status of all teeth was assessed using the periapical index score.
The average number of teeth per patient in the diabetic and control groups was 21.9 and 24.6 teeth, respectively (P = .012). AP in one or more teeth was found in 37 diabetic patients (74%) and in 21 control subjects (42%) (odds ratio = 3.9, P = .002). One or more root-filled teeth were found in 35 (70%) and 25 (50%) of diabetic and control subjects, respectively (odds ratio = 2.3, P = .043). Among diabetic patients with root-filled teeth, 16 (46%) had AP affecting at least one treated tooth. Among controls with root-filled teeth, 6 (24%) had AP affecting at least one treated tooth (P > .05). Adjusting for teeth number, multivariate logistic regression analysis showed that periapical status (odds ratio = 3.3, P = .0071) and the number of root-filled teeth (odds ratio = 1.7; P = .0035) were significantly associated with diabetic status.
The results showed that in adult patients, type 2 DM is significantly associated with an increased prevalence of AP and endodontic treatment.
本研究旨在调查一定样本量的成年 2 型糖尿病患者和对照组中根尖周病（AP）和根管治疗的流行情况。
在一项横断面研究中，检查了 50 名患有 2 型糖尿病（DM）病史且病情控制良好的成年患者（研究组）和 50 名无 DM 病史的年龄和性别匹配的受试者（对照组）的放射记录。使用根尖指数评分评估所有牙齿的根尖状态。
糖尿病组和对照组患者的平均牙齿数分别为 21.9 颗和 24.6 颗（P =.012）。在 37 名糖尿病患者（74%）和 21 名对照组受试者（42%）中发现了一颗或多颗牙齿的 AP（比值比=3.9，P =.002）。在 35 名（70%）和 25 名（50%）糖尿病和对照组受试者中发现了一颗或多颗根管治疗的牙齿（比值比=2.3，P =.043）。在接受根管治疗的糖尿病患者中，16 名（46%）至少有一颗治疗牙发生 AP。在接受根管治疗的对照组中，有 6 名（24%）至少有一颗治疗牙发生 AP（P>.05）。在调整牙齿数量后，多变量逻辑回归分析显示，根尖状态（比值比=3.3，P =.0071）和根管治疗牙齿数量（比值比=1.7；P =.0035）与糖尿病状态显著相关。
结果表明，在成年患者中，2 型糖尿病与 AP 和根管治疗的患病率增加显著相关。
