Department of Endodontics, Faculty of Dentistry, Estácio de Sá University, Rio de Janeiro, Rio de Janeiro.
J Endod. 2012 Mar;38(3):297-300. doi: 10.1016/j.joen.2011.11.001. Epub 2011 Dec 22.
This cross-sectional study evaluated the prevalence of apical periodontitis (AP) and endodontic treatment in type 2 diabetic individuals as compared with nondiabetics from an adult Brazilian population.
Full-mouth radiographs from 30 type 2 diabetic and 60 age- and sex-matched nondiabetic individuals were examined, and the presence of AP lesions in untreated and root canal-treated teeth was recorded. The number of teeth and the prevalence of root canal treatment were also evaluated.
AP was significantly more present in teeth from diabetic individuals (98/652, 15%) than in nondiabetic controls (162/1,368, 12%) (P = .05). A separate analysis of untreated and treated teeth revealed that significance was mostly because of the prevalence of AP in untreated teeth, which was 10% in diabetics and 7% in nondiabetics (P = .03). No significant difference between diabetics and nondiabetics was observed for the other parameters under study, including the prevalence of AP in root canal-treated teeth, the number of teeth in the oral cavity, the number of treated teeth per individual, the number of individuals with at least 1 AP lesion or 1 root canal treatment, and the number of teeth with AP per individual (P > .05).
AP was significantly more prevalent in untreated teeth from type 2 diabetics. This suggests that diabetes may serve as a disease modifier of AP in the sense that individuals with diabetes can be more prone to develop primary disease. However, findings do not confirm that diabetes may influence the response to root canal treatment because treated teeth had no increased prevalence of AP when compared with controls.
本横断面研究评估了与非糖尿病者相比，巴西成年人群中 2 型糖尿病个体的根尖周炎（AP）和根管治疗的患病率。
检查了 30 名 2 型糖尿病患者和 60 名年龄和性别匹配的非糖尿病患者的全口曲面断层片，并记录了未治疗和根管治疗牙齿中 AP 病变的存在情况。还评估了牙齿数量和根管治疗的患病率。
糖尿病患者（98/652，15%）未治疗牙齿中 AP 的存在明显高于非糖尿病对照组（162/1,368，12%）（P=0.05）。对未治疗和治疗牙齿进行的单独分析表明，这种差异主要是由于未治疗牙齿中 AP 的患病率，糖尿病患者为 10%，非糖尿病患者为 7%（P=0.03）。对于研究中的其他参数，包括根管治疗牙齿中 AP 的患病率、口腔内牙齿数量、每位患者的治疗牙齿数量、每位患者至少有 1 个 AP 病变或 1 个根管治疗的患者数量以及每位患者的 AP 牙齿数量，糖尿病患者和非糖尿病患者之间没有观察到显著差异（P＞0.05）。
2 型糖尿病患者的未治疗牙齿中 AP 的患病率明显更高。这表明糖尿病可能是 AP 的疾病修饰因子，即糖尿病患者更容易发生原发性疾病。然而，研究结果并不能证实糖尿病可能会影响根管治疗的反应，因为与对照组相比，治疗后的牙齿中 AP 的患病率并没有增加。
