肾母细胞瘤和神经母细胞瘤——组织学与预后

Nephroblastoma and neuroblastoma--histology and prognosis.

作者信息

Meister P, Middeke M, Selbmann H K

出版信息

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978 Oct 30;92(3):315-26. doi: 10.1007/BF00461655.

Abstract

Statistically evaluating the influence of a histological grading, respectively of morphological differences on prognosis of nephroblastomas and neuroblastomas, better chances for survival become evident not only for earlier clinical stages, but also for nephroblastomas with high differentiation, or neuroblastomas with signs for differentiation. Only for neuroblastomas a relevant predeliction of tumors with signs of differentiation for the early clinical stage I is present. Combined subclassification according to clinical stages and histological grades results in 3 risk groups with different chances for survival. These 3 groups may play a role for specific therapeutic considerations.

摘要

通过统计学评估组织学分级以及形态学差异分别对肾母细胞瘤和神经母细胞瘤预后的影响，结果表明，不仅早期临床阶段的患者生存机会更大，高分化肾母细胞瘤或有分化迹象的神经母细胞瘤患者的生存机会也更大。仅对于神经母细胞瘤，有分化迹象的肿瘤在临床I期早期有明显的倾向性。根据临床分期和组织学分级进行联合亚分类，可得出3个具有不同生存机会的风险组。这3个组可能在特定的治疗考量中发挥作用。