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细菌大小的颗粒经缝合的人眼角膜透明切口流入实验室模型。

Bacterial-sized particle inflow through sutured clear corneal incisions in a laboratory human model.

机构信息

Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

出版信息

J Cataract Refract Surg. 2011 Jun;37(6):1140-6. doi: 10.1016/j.jcrs.2010.11.042. Epub 2011 Apr 15.

DOI:10.1016/j.jcrs.2010.11.042
PMID:21497050
Abstract

PURPOSE

To determine the effectiveness of a single radial suture placement in 2 clear corneal incision (CCI) configurations in preventing inflow of bacterial-sized particles.

SETTING

Wilmer Eye Institute, Baltimore, Maryland, USA.

DESIGN

Experimental study.

METHODS

Ten human globes were used. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were inserted through the limbus 120 degrees apart. Four incision-suture combinations were evaluated sequentially in each cornea. All incisions had the same dimensions (2.75 mm width, 3.00 mm length). Two incisions were single plane, and 2 were biplane. One incision from each configuration was left unsutured, and the other was sutured (10-0 nylon). With a preset 10 mm Hg intraocular pressure (IOP), India ink was applied to the incision site and a sudden IOP fluctuation was induced. Inflow was outlined and measured by planimetry.

RESULTS

There was a significant increase in area and linear distance of India-ink inflow after pressure challenge in all groups (P < .05), but with important differences among them. When the sutured and unsutured groups from each CCI were compared, there was a significantly smaller area of inflow in the 2-step unsutured group (P < .05). The linear inflow was higher in both sutured groups; however, the difference was significant for the 2-step incision configuration only (P < .05).

CONCLUSIONS

A single radial suture reduced the area of inflow of bacterial-sized particles but increased the linear distance of inflow in single-plane 3.0 mm incisions. Suture placement in a stepped incision increased inflow of bacterial-sized particles.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

确定两种不同的巩膜切口(CCI)中,单一放射状缝线放置在预防细菌大小颗粒流入的效果。

设置

美国马里兰州巴尔的摩威尔默眼科研究所。

设计

实验研究。

方法

使用 10 个人眼球。两个 25 号针头通过角膜缘以 120 度的间隔连接到生理盐水袋和数字压力计。在每只角膜中顺序评估四种切口缝线组合。所有切口的尺寸相同(2.75 毫米宽,3.00 毫米长)。两个切口为单平面,两个为双平面。每个配置的一个切口未缝合,另一个缝合(10-0 尼龙)。在预设的 10mmHg 眼内压(IOP)下,将印度墨水涂抹在切口部位并突然引起 IOP 波动。通过平面测量法勾勒并测量流入量。

结果

在所有组中,压力挑战后印度墨水流入的面积和线性距离均显着增加(P<.05),但它们之间存在重要差异。当比较每个 CCI 的缝合和未缝合组时,未缝合的 2 步组的流入面积明显较小(P<.05)。两个缝合组的线性流入均较高;然而,仅对于 2 步切口构型,差异具有统计学意义(P<.05)。

结论

单一放射状缝线减少了细菌大小颗粒的流入面积,但增加了单平面 3.0 毫米切口的流入线性距离。阶梯式切口缝线放置增加了细菌大小颗粒的流入。

财务披露

没有作者对任何材料或方法有财务或专有利益。

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