Hwang Sunjin, Kim Moonsu, Yoon Jooyoung, Hong Eun Hee, Shin Yong Un, Kang Min Ho
Department of Ophthalmology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri 11923, Republic of Korea.
J Clin Med. 2025 Jun 10;14(12):4091. doi: 10.3390/jcm14124091.
This study introduces a novel quantitative method-groove loss time (GLT)-to objectively assess wound leakage following cataract surgery. In this prospective, single-center study, 70 eyes of 70 patients undergoing cataract surgery via CCI were enrolled. Wound sealing was evaluated by measuring the GLT, defined as the duration the stromal groove remains visible after corneal hydration. GLT was categorized into five grades: 'water-tight' (>10 s), 'excellent' (>5 s), 'good' (3-5 s), 'bad' (1-2 s), and 'poor' (<1 s). Intraocular pressure (IOP) was recorded at four time points: preoperatively, immediately post-surgery, 3-4 h postoperatively, and on postoperative day one. In select cases, anterior segment optical coherence tomography (AS-OCT) was used to confirm wound architecture. All patients demonstrated a GLT longer than 5 s, corresponding to water-tight or excellent wound sealing. Mean IOP values were 16.08 ± 3.61 mmHg preoperatively, 29.48 ± 11.13 mmHg immediately post-surgery, 16.38 ± 5.45 mmHg at 3-4 h, and 16.65 ± 4.36 mmHg on the day after surgery. No cases of postoperative endophthalmitis, anterior chamber loss, or hypotony were observed. The GLT method provides a simple, objective, and effective tool for evaluating wound integrity in CCIs, ensuring optimal sealing and enhancing postoperative safety.
本研究引入了一种新型定量方法——沟槽消失时间(GLT),以客观评估白内障手术后的伤口渗漏情况。在这项前瞻性单中心研究中,纳入了70例接受白内障超声乳化吸除术(CCI)的患者的70只眼。通过测量GLT来评估伤口封闭情况,GLT定义为角膜水化后基质沟槽仍可见的持续时间。GLT分为五个等级:“水密”(>10秒)、“优”(>5秒)、“良”(3 - 5秒)、“差”(1 - 2秒)和“劣”(<1秒)。在四个时间点记录眼压(IOP):术前、术后即刻、术后3 - 4小时以及术后第一天。在部分病例中,使用眼前节光学相干断层扫描(AS - OCT)来确认伤口结构。所有患者的GLT均超过5秒,对应水密或良好的伤口封闭。术前平均眼压值为16.08±3.61 mmHg,术后即刻为29.48±11.13 mmHg,术后3 - 4小时为16.38±5.45 mmHg,术后第一天为16.65±4.36 mmHg。未观察到术后眼内炎、前房消失或低眼压病例。GLT方法为评估白内障超声乳化吸除术中的伤口完整性提供了一种简单、客观且有效的工具,确保了最佳的封闭效果并提高了术后安全性。