Chemistry Research Centre, S.S.M.R.V. Degree College, Jayanagar, Bangalore-560041, India.
Bioelectrochemistry. 2011 Jun;81(2):104-8. doi: 10.1016/j.bioelechem.2011.03.004. Epub 2011 Mar 22.
Graphene is chemically synthesized by solvothermal reduction of colloidal dispersions of graphite oxide. Graphite electrode is modified with functionalized-graphene for electrochemical applications. Electrochemical characterization of functionalized-graphene modified graphite electrode (FGGE) is carried out by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The behavior of FGGE towards ascorbic acid (AA), dopamine (DA) and uric acid (UA) has been investigated by CV, differential pulse voltammetry (DPV) and chronoamperommetry (CA). The FGGE showed excellent catalytic activity towards electrochemical oxidation of AA, DA and UA compared to that of the bare graphite electrode. The electrochemical oxidation signals of AA, DA and UA are well separated into three distinct peaks with peak potential separation of 193mv, 172mv and 264mV between AA-DA, DA-UA and AA-UA respectively in CV studies and the corresponding peak potential separations in DPV mode are 204mv, 141mv and 345mv. The FGGE is successfully used for the simultaneous detection of AA, DA and UA in their ternary mixture and DA in serum and pharmaceutical samples. The excellent electrocatalytic behavior of FGGE may lead to new applications in electrochemical analysis.
石墨烯是通过胶体分散的氧化石墨的溶剂热还原化学合成的。石墨电极用功能化石墨烯进行修饰，用于电化学应用。通过循环伏安法（CV）和电化学阻抗谱（EIS）对功能化石墨烯修饰石墨电极（FGGE）进行电化学表征。通过 CV、差分脉冲伏安法（DPV）和计时安培法（CA）研究了 FGGE 对抗坏血酸（AA）、多巴胺（DA）和尿酸（UA）的行为。与裸石墨电极相比，FGGE 对 AA、DA 和 UA 的电化学氧化表现出优异的催化活性。在 CV 研究中，AA、DA 和 UA 的电化学氧化信号很好地分离成三个不同的峰，AA-DA、DA-UA 和 AA-UA 之间的峰电位分离分别为 193mV、172mV 和 264mV，相应的 DPV 模式下的峰电位分离分别为 204mV、141mV 和 345mV。FGGE 成功地用于同时检测 AA、DA 和 UA 的三元混合物以及血清和药物样品中的 DA。FGGE 的优异电催化行为可能会导致在电化学分析中的新应用。
