Diebold B, Cohen A, Zelinsky R, Raffoul H, Foucher A, Guermonprez J L, Peronneau P
Unité INSERM 256, Hopital Broussais, Paris, France.
Eur Heart J. 1990 Nov;11 Suppl G:79-86. doi: 10.1093/eurheartj/11.suppl_g.79.
Pulsed Doppler tracings of the mitral inflow are often proposed to describe left ventricular function during filling in hypertensive patients. The tracings are determined by the complex interaction of left atrial pressure and left ventricular relaxation, diastolic compliance and contractility of the left atrium. They strongly depend on preload and, thus, do not allow precise characterization of the left ventricle. In addition, they vary with age, heart rate and the site of measurement. The modifications caused by the presence of hypertensive hypertrophy are not specific: similar changes are seen for example, in the presence of hypertrophic cardiomyopathy or coronary heart disease, but are absent in highly trained athletes in spite of very significant physiologic hypertrophy.
二尖瓣流入道的脉冲多普勒描记图常被用于描述高血压患者心室充盈期的左心室功能。这些描记图由左心房压力与左心室舒张、舒张期顺应性以及左心房收缩性之间的复杂相互作用所决定。它们在很大程度上取决于前负荷，因此无法精确表征左心室。此外，它们会随年龄、心率和测量部位而变化。高血压性肥厚所引起的改变并不具有特异性：例如，在肥厚型心肌病或冠心病患者中也可见到类似变化，而在训练有素的运动员中，尽管存在非常显著的生理性肥厚，但却没有这些变化。
