Tang He-han, Yue Qiang, Chen Jia, Gong Qi-yong, Lü Su, Song Bin
Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Mar;42(2):269-72.
To investigate the effect of space saturation technique on the quality of proton magnetic resonance spectroscopy (1 H-MRS) for amygdala.
22 healthy volunteers were enrolled and scanned at a 3.0T MR scanner. Single voxel H-MRS of amygdala with and without space saturation bands around the region of interest was performed using point-resolved spectroscopy series (PRESS, TR/TE = 1500/30 ms). Raw spectral data were processed and signal-to-noise ratio of creatine (Cr-SNR), water-suppression level, full width at half maximum (FWHM) and root mean square (RMS) noise were obtained and compared between groups with and without saturation bands.
The Cr-SNR of spectra without and with saturation bands was 15.506 +/- 6.623 and 22.935 +/- 7.270, respectively [increased by (47.9% +/- 24.94%), P < 0.001]. The water-suppression level of spectra without and with saturation bands was (93.888% +/- 1.079%) and (95.722% +/- 0.461%), respectively [increased by (1.95% +/- 0.68%), P < 0.001]. The FWHM of spectra without and with saturation bands was 7.00 +/- 1.113 and 6.82 +/- 1.181, respectively [decreased by (2.57% +/- 1.12%), P > 0.053. The RMS noise of spectra without and with saturation bands was 0.606 +/- 0.0615 and 0.589 +/- 0.0470, respectively [reduced by (2.81% +/- 1.68%), P > 0.053.
Application of space saturation technique significantly elevates the Cr-SNR and the water-suppression level, and thus improves the spectral quality of amygdala without additional scanning time.
探讨空间饱和技术对杏仁核质子磁共振波谱（1H-MRS）质量的影响。
招募22名健康志愿者，在3.0T磁共振扫描仪上进行扫描。使用点分辨波谱序列（PRESS，TR/TE = 1500/30 ms）对杏仁核进行单像素H-MRS扫描，分别在感兴趣区域周围设置和不设置空间饱和带。对原始光谱数据进行处理，获得肌酸的信噪比（Cr-SNR）、水抑制水平、半高宽（FWHM）和均方根（RMS）噪声，并对设置和未设置饱和带的两组数据进行比较。
未设置饱和带和设置饱和带的光谱的Cr-SNR分别为15.506±6.623和22.935±7.270[增加了（47.9%±24.94%），P<0.001]。未设置饱和带和设置饱和带的光谱的水抑制水平分别为（93.888%±1.079%）和（95.722%±0.461%）[增加了（1.95%±0.68%），P<0.001]。未设置饱和带和设置饱和带的光谱的FWHM分别为7.00±1.113和6.82±1.181[降低了（2.57%±1.12%），P>0.053]。未设置饱和带和设置饱和带的光谱的RMS噪声分别为0.606±0.0615和0.589±0.0470[降低了（2.81%±1.68%），P>0.053]。
空间饱和技术的应用显著提高了Cr-SNR和水抑制水平，从而在不增加扫描时间的情况下改善了杏仁核的光谱质量。
