[杏仁核的磁共振波谱分析：方法学研究]

[MR spectroscopy of amygdala: investigation of methodology].

作者信息

Tang Hehan, Yue Qiang, Gong Qiyong

机构信息

Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2013 Aug;30(4):714-8.

PMID:24059042

Abstract

This study was aimed to optimize the methods of magnetic resonance spectroscopy (MRS) to improve its quality in amygdala. Forty-three volunteers were examined at right and left amygdala using stimulated-echo acquisition mode (STEAM), and point-resolved spectroscopy series (PRESS) with and without saturation bands. The Cr-SNR, water-suppression level, water full width at half maximum (FWHM) and RMS noise of three sequences were compared. The results showed that (1) the Cr-SNR and water-suppression lelvel of PRESS with saturation bands were better than that of PRESS without saturation bands and STEAM (P<0.001); (2) the left and right RMS noise was significantly different both using PRESS with saturation bands and using STEAM (P<0.05); (3) there was a positive, significant correlation between Cr-SNR and voxel size (P<0.05). Therefore, PRESS with saturation bands is better than PRESS without saturation bands or STEAM for the spectroscopy of amygdala. It is also useful to make the voxel as big as possible to improve the spectral quality.

摘要

本研究旨在优化磁共振波谱（MRS）方法，以提高杏仁核区域的MRS质量。对43名志愿者的左右杏仁核进行了检查，采用激励回波采集模式（STEAM）以及带有和不带有饱和带的点分辨波谱序列（PRESS）。比较了三种序列的肌酸（Cr）信噪比、水抑制水平、水半高宽（FWHM）和均方根噪声（RMS）。结果表明：（1）带有饱和带的PRESS序列的Cr信噪比和水抑制水平优于不带饱和带的PRESS序列和STEAM序列（P<0.001）；（2）使用带有饱和带的PRESS序列和STEAM序列时，左右两侧的RMS噪声均有显著差异（P<0.05）；（3）Cr信噪比与体素大小之间存在正相关且具有显著性（P<0.05）。因此，对于杏仁核波谱分析，带有饱和带的PRESS序列优于不带饱和带的PRESS序列或STEAM序列。尽可能增大体素大小对提高波谱质量也很有帮助。