Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Curr Eye Res. 2011 May;36(5):422-8. doi: 10.3109/02713683.2010.534574.
To investigate the influence of positional deviations on the rebound tonometer measurement.
Ten white rabbits were used. A bottle of balanced salt solution was connected to the anterior chamber, and the IOP was altered by changing the height of the bottle. A pressure transducer was also connected to the anterior chamber. The IOP was measured by the rebound tonometer (RBT), the Tonopen XL, and the Perkins handheld applanation tonometer at optimal conditions and compared each tonometer. Then, the effect of placing the RBT probe at different distances, different lateral positions, and different angles to the cornea on the IOP was determined.
The RBT had the lowest variance in all three tonometers. The IOP measured with the RBT was not significantly altered when the distance from the cornea was 4 to 8 mm, or when the probe was displaced 2 mm to the central cornea, or when the probe was placed at an angle of 20° from the central axis.
The low variance of the RBT measurements and the non-significant changes in the IOP when the probe of the RBT was not on the central axis indicate that the RBT is useful for animal models of glaucoma. Further studies examining its use (repeatability and reliability) in human infants whose eyes and head are usually moving are required.
研究位置偏差对回弹眼压计测量的影响。
使用 10 只白兔。在前房连接一瓶平衡盐溶液,通过改变瓶子的高度来改变眼压。前房还连接有一个压力传感器。在最佳条件下,使用回弹眼压计(RBT)、Tonopen XL 和 Perkins 手持式压平眼压计测量眼压,并对每种眼压计进行比较。然后,确定将 RBT 探头放置在距角膜不同距离、不同侧方位置和不同角度对眼压的影响。
在三种眼压计中,RBT 的方差最小。当角膜距离为 4 至 8mm 时,或当探头向角膜中央偏移 2mm 时,或当探头与中央轴成 20°角放置时,RBT 测量的眼压没有明显变化。
RBT 测量的低方差和 RBT 探头不在中央轴线上时眼压无显著变化表明,RBT 可用于青光眼动物模型。需要进一步研究其在眼球和头部通常在移动的人类婴儿中的应用(重复性和可靠性)。