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[控制小鼠体内抑制巨噬细胞向白色念珠菌抗原和结核菌素迁移的一种因子产量的基因的表型表达]

[The phenotypic expression of the genes controlling the yield of a factor suppressing macrophage migration to Candida albicans antigens and tuberculin in mice].

作者信息

Vorob'ev K V, Gankovskaia L V, Koval'chuk L V, Vasil'ev O D

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1990 Oct(10):109-12.

PMID:2150140
Abstract

The regulation of the synthesis of factor inhibiting the migration of macrophages in response to C. albicans antigen in CBA (H-2k) and C57BL/6 (H-2b) mice has been studied. The low level of macrophage migration inhibition factor in response to this antigen is due to the existence of cyclophosphamide-inhibited specific suppressors. Differences between various strains of mice ensue from different activity of suppressors of thymic origin, whose nature has been revealed as the result of the transfer of marrow cells treated with anti-Thy-1 serum.

摘要

已对CBA(H-2k)和C57BL/6(H-2b)小鼠中,针对白色念珠菌抗原的巨噬细胞迁移抑制因子合成的调节进行了研究。对该抗原的巨噬细胞迁移抑制因子水平较低是由于存在环磷酰胺抑制的特异性抑制因子。不同品系小鼠之间的差异源于胸腺来源抑制因子的不同活性,通过用抗Thy-1血清处理的骨髓细胞转移,揭示了其性质。

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1
[The phenotypic expression of the genes controlling the yield of a factor suppressing macrophage migration to Candida albicans antigens and tuberculin in mice].[控制小鼠体内抑制巨噬细胞向白色念珠菌抗原和结核菌素迁移的一种因子产量的基因的表型表达]
Zh Mikrobiol Epidemiol Immunobiol. 1990 Oct(10):109-12.
2
[Nature of the cells regulating the production of a migration inhibition factor in C57BL/6 strain mice with low response to Candida albicans antigen].
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[Role of suppressor cells in the regulation of production of the macrophage migration inhibitory factor in mice with opposite reaction to tuberculin and Candida albicans antigens].[抑制细胞在对结核菌素和白色念珠菌抗原有相反反应的小鼠中巨噬细胞移动抑制因子产生调节中的作用]
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Characterization of Candida albicans mannan-induced, mannan-specific delayed hypersensitivity suppressor cells.白色念珠菌甘露聚糖诱导的、甘露聚糖特异性迟发型超敏反应抑制细胞的特性研究
Infect Immun. 1990 Aug;58(8):2613-20. doi: 10.1128/iai.58.8.2613-2620.1990.