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[对白假丝酵母菌的迟发型超敏反应]

[Delayed hypersensitivity to Candida albicans].

作者信息

Frolova E V, Prokrovskaia O L, Karaev Z O

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1990 Aug(8):103-7.

PMID:2238997
Abstract

Conditions and factors influencing the formation of delayed hypersensitivity (DH) to yeast-like fungi of the species C. albicans under experimental conditions have been studied. The intensity of this reaction has been found to depend on the dose and method used for infecting mice, the time of the test and the qualitative state of fungal cells. As the result of this study, the infectious model of DH to C. albicans has been proposed. This model may be used for the study of the influence of different exogenous and endogenous factors of cell-mediated immune response to candidiasis.

摘要

在实验条件下,对影响白色念珠菌这一物种的酵母样真菌迟发型超敏反应(DH)形成的条件和因素进行了研究。已发现这种反应的强度取决于感染小鼠所使用的剂量和方法、测试时间以及真菌细胞的质量状态。作为这项研究的结果,提出了对白色念珠菌迟发型超敏反应的感染模型。该模型可用于研究细胞介导的免疫反应对念珠菌病的不同外源性和内源性因素的影响。

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