Escola Nacional de Saúde Pública, Universidade Federal Fluminense, Rio de Janeiro, RJ - Brazil.
Arq Bras Cardiol. 2011 Jun;96(6):471-6. doi: 10.1590/s0066-782x2011005000048. Epub 2011 Apr 15.
Adiponectin is considered an important factor in the pathogenesis of cardiovascular and metabolic diseases, due to its anti- atherogenic and anti-inflammatory properties. Few studies, however, have suggested the existence of a direct association between adiponectin levels and cardiorespiratory fitness and physical activity levels.
To verify the influence of the nutritional status and cardiorespiratory fitness on plasma adiponectin levels in adult men.
A total of 250 subjects, all in active duty in the Brazilian Army (BA), with a mean age of 42,6 ± 4,8 years volunteered to participate in the study. Plasma levels of adiponectin were measured, as well as body mass, height, waist circumference (WC), fat percentage by hydrostatic weighing and VO(2max) by ergospirometry. A questionnaire was used to obtain the characteristics of the physical training performed by the individuals.
The sample showed that 121 (48%) individuals were overweight and 36 (14%) were obese. Moreover, 66 individuals (27%) had a body fat percentage > 25% and 26,7% had a WC > 94 cm. Overweight and obese individuals had significantly lower adiponectin levels than those with an adequate nutritional status. Individuals at the highest tertile of VO(2max) had higher adiponectin levels than the others. The adiponectin levels were positively correlated with the total weekly physical training time and VO(2max) and inversely correlated with body mass, BMI and WC. The correlation between adiponectin levels and VO(2max) did not remain significant after being adjusted for BMI and WC.
Individuals with better cardiorespiratory fitness and normal nutritional status seem to present healthier levels of adiponectin.
脂联素因其抗动脉粥样硬化和抗炎特性，被认为是心血管和代谢疾病发病机制中的一个重要因素。然而，很少有研究表明脂联素水平与心肺功能适应性和身体活动水平之间存在直接关联。
验证营养状况和心肺功能适应性对成年男性血浆脂联素水平的影响。
共有 250 名受试者，均为巴西陆军现役军人，平均年龄为 42.6 ± 4.8 岁，自愿参加研究。测量了血浆脂联素水平，以及体重、身高、腰围（WC）、静水称重法测定的体脂肪百分比和运动心肺功能测试（ergospirometry）测定的最大摄氧量（VO2max）。使用问卷获得个体进行的身体训练特征。
该样本中 121 人（48%）超重，36 人（14%）肥胖。此外，66 人（27%）体脂肪百分比>25%，26.7%的人 WC>94cm。超重和肥胖个体的脂联素水平明显低于营养状况良好的个体。VO2max 最高三分位组的个体脂联素水平较高。脂联素水平与每周总体力训练时间和 VO2max 呈正相关，与体重、BMI 和 WC 呈负相关。调整 BMI 和 WC 后，脂联素水平与 VO2max 之间的相关性不再显著。
心肺功能适应性较好且营养状况正常的个体似乎具有更健康的脂联素水平。
