Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, Brasil.
Cad Saude Publica. 2011;27 Suppl 1:S79-92. doi: 10.1590/s0102-311x2011001300009.
The aim of this study was to evaluate survival time for AIDS patients 13 years and older in the South and Southeast regions of Brazil, according to socio-demographic, clinical, and epidemiological characteristics. The sample was selected from all cases diagnosed in 1998 and 1999 and notified to the Epidemiological Surveillance System of the National STD/AIDS Program. Use of a questionnaire allowed analyzing 2,091 patient charts. Based on the Kaplan-Meier method, estimated survival was at least 108 months after diagnosis in 59.5% of patients in the Southeast and 59.3% in the South. Cox regression models showed, in both regions, an increase in survival in patients on antiretroviral therapy, those classified as AIDS cases according to the CD4 T-cell criterion, females, and those with more schooling. Other factors associated with longer survival in the Southeast were: white skin color, no history of tuberculosis since the AIDS diagnosis, negative hepatitis B serology, and access to a multidisciplinary health team. In the South, age below 40 years was associated with longer survival.
本研究旨在评估巴西南部和东南部年龄在 13 岁及以上的艾滋病患者的存活时间,依据为社会人口学、临床和流行病学特征。该样本选自 1998 年和 1999 年诊断并向国家性传播疾病/艾滋病规划的流行病学监测系统报告的所有病例。使用问卷分析了 2091 份患者病历。基于 Kaplan-Meier 方法,在东南部和南部,诊断后至少有 59.5%的患者存活时间超过 108 个月。Cox 回归模型显示,在两个地区,接受抗逆转录病毒治疗、根据 CD4 T 细胞标准分类为艾滋病病例、女性和受教育程度较高的患者,其存活时间均有所增加。与东南部地区存活时间较长相关的其他因素包括:白人肤色、艾滋病诊断以来无结核病病史、乙型肝炎血清学阴性以及获得多学科保健团队的服务。在南部,年龄低于 40 岁与存活时间延长相关。