巴西南部和东南部艾滋病患者的生存率及其与教育水平和种族/肤色的关联：一项队列研究，1998 - 1999年

Survival of patients with AIDS and association with level of education level and race/skin color in South and Southeast Brazil: a cohort study, 1998-1999.

作者信息

Melo Márcio Cristiano de, Mesquita Fernanda Coutinho, Barros Marilisa Berti de Azevedo, La-Rotta Ehidee Isabel Gomez, Donalisio Maria Rita

机构信息

Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Campinas, SP, Brasil.

Pontifícia Universidade Católica de Campinas, Faculdade de Medicina, Campinas, SP, Brasil.

出版信息

Epidemiol Serv Saude. 2019;28(1):e2018047. doi: 10.5123/S1679-49742019000100012. Epub 2019 Apr 8.

DOI:10.5123/S1679-49742019000100012

PMID:30970069

Abstract

OBJECTIVE

to analyze the survival of people with AIDS and association with schooling and race/skin color.

METHODS

this was a retrospective cohort study of people diagnosed with AIDS between 1998 and 1999, in the South and Southeast regions of Brazil. We used survival analysis (Kaplan-Meier method), stratified by schooling and race/skin color and multivariate analysis was performed using Cox regression.

RESULTS

the study included 2,091 people who had survived at 60 months, with 65% survival among White participants and 62% among Black/brown participants. Irregular use of antiretroviral (HR=11.2 - 95%CI8.8;14.2), and age ≥60 years (HR=2.5 - 95%CI1.4;4.4) were related to lower survival; schooling >8 years (HR=0.4 - 95%CI0.3;0.6) and being female (HR=0.6 - 95%CI0.5;0.8) were positively related to survival; those with less schooling had lower survival.

CONCLUSION

lower schooling levels overlap race/skin color differences in relation to survival; these inequalities explain the differences found, despite the policies on universal access to antiretroviral.

摘要

目的

分析艾滋病患者的生存率及其与受教育程度和种族/肤色的关系。

方法

这是一项对1998年至1999年期间在巴西南部和东南部地区被诊断为艾滋病的患者进行的回顾性队列研究。我们采用生存分析（Kaplan-Meier方法），按受教育程度和种族/肤色分层，并使用Cox回归进行多变量分析。

结果

该研究纳入了2091名存活60个月的患者，白人参与者的生存率为65%，黑人/棕色人种参与者的生存率为62%。抗逆转录病毒药物使用不规律（HR=11.2 - 95%CI 8.8;14.2）以及年龄≥60岁（HR=2.5 - 95%CI 1.4;4.4）与较低的生存率相关；受教育年限>8年（HR=0.4 - 95%CI 0.3;0.6）以及女性（HR=0.6 - 95%CI 0.5;0.8）与生存率呈正相关；受教育程度较低者生存率较低。