Kuokkanen K
Acta Allergol. 1977 Oct;32(5):316-20. doi: 10.1111/j.1398-9995.1977.tb02573.x.
The effect and tolerance of a new antihistamine, HC 20-511, in daily doses of 2 and 4 mg was compared with cyproheptadine (Periactin) 8 mg daily in 50 cases of chronic urticaria. HC 20-511 4 mg daily proved to be the most effective, rapid and long-lasting. HC 20-511 had less sedative effect than cyproheptadine, but both possessed the same appetite-stimulating effect. However, this was not noted with the smaller dosage of HC 20-511.
将一种每日剂量为2毫克和4毫克的新型抗组胺药HC 20 - 511与每日8毫克的赛庚啶（periactin）在50例慢性荨麻疹患者中进行疗效和耐受性比较。结果证明，每日服用4毫克的HC 20 - 511效果最佳，起效迅速且作用持久。HC 20 - 511的镇静作用比赛庚啶小，但两者都有相同的刺激食欲的作用。然而，较小剂量的HC 20 - 511未观察到这种情况。
