Modelling and Economics Unit, Centre for Infections, Health Protection Agency, London, UK.
Pharmacoeconomics. 2011 May;29(5):371-86. doi: 10.2165/11539960-000000000-00000.
The number of economic evaluations related to infectious disease topics has increased over the last 2 decades. However, many such evaluations rely on models that do not take into account unique features of infectious diseases that can affect the estimated value of interventions against them. These include their transmissibility from infected to susceptible individuals, the possibility of acquiring natural immunity following recovery from infection and the uncertainties that arise as a result of their complex natural history and epidemiology. Modellers conducting economic evaluations of infectious disease interventions need to know the main features of different types of infectious disease models, the situations in which they should be applied and the effects of model choices on the cost effectiveness of interventions.
在过去的 20 年里，与传染病相关的经济评估数量有所增加。然而，许多此类评估依赖的模型并未考虑到传染病的独特特征，这些特征可能会影响针对传染病干预措施的估计价值。这些特征包括从感染者传播给易感者的传染性、感染康复后获得自然免疫力的可能性，以及由于其复杂的自然史和流行病学而产生的不确定性。对传染病干预措施进行经济评估的建模人员需要了解不同类型传染病模型的主要特征、它们应该应用的情况，以及模型选择对干预措施成本效益的影响。
