Costellati L, Guglielmin A M, Vistoli O, Carboni G P, Rambaldi R
Servizio di Medicina Preventiva ed Igiene del Lavoro, U.S.L. n. 27, Bologna Ovest.
Med Lav. 1990 Jul-Aug;81(4):296-300.
Patch tests were performed on 43 workers employed in an animal fodder plant, a typical dust-laden environment. The aim of the study was to establish and assess the incidence of preclinical sensitization to the substances used, some of which are well known allergens, and identify which of these were mostly responsible. On the whole, the tests did not reveal any major reaction to the allergens used, nor polysensitization. However, an unexpected number of cases was sensitized to phenothiazine, a substance that had not been use for the preceding two years. This observation is of interest since phenothiazine is scarcely allergenic and skin eruptions occur only after photosensitization.
对一家动物饲料厂的43名工人进行了斑贴试验,该厂是一个典型的多尘环境。该研究的目的是确定和评估对所用物质的临床前致敏发生率,其中一些物质是众所周知的过敏原,并确定其中哪些是主要原因。总体而言,测试未发现对所用过敏原的任何重大反应,也未发现多致敏现象。然而,有出乎意料数量的病例对吩噻嗪致敏,吩噻嗪是一种在之前两年未使用过的物质。这一观察结果很有意思,因为吩噻嗪几乎不会引起过敏,只有在光敏反应后才会出现皮肤疹。