Department of Internal Medicine, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA.
Clin Transplant. 2011 Sep-Oct;25(5):E487-90. doi: 10.1111/j.1399-0012.2011.01468.x. Epub 2011 Apr 19.
The purpose of the study was to characterize differences in donor and recipient relationships between African American (AA) and Caucasian living kidney donors.
Data from all successful living kidney donors at a single institution between 1991 and 2009 were reviewed. Relationships between donor and recipient were categorized and between-group comparisons performed.
The study sample consisted of 73 (18%) AA and 324 Caucasian living kidney donors. The distribution of donor-recipient relationships differed significantly between AA and Caucasians. AA donors were more likely to be related to the recipient (88% vs. 74%, p = 0.007) than Caucasians. AA donors were more likely to participate in child to parent donation and were less likely to participate in parent to child donation or to donate to unrelated individuals. Sibling and spousal donations were similar in both groups. Caucasian donors were more likely to be unrelated to the recipient than AA donors.
Differences exist in donor-recipient relationships between AA and Caucasian living kidney donors. Future studies exploring cultural differences and family dynamics may provide targeted recruitment strategies for AA and Caucasian living kidney donors. Living unrelated kidney transplantation appears to be a potential growth area for living kidney donation in AA.
本研究旨在描述非裔美国人和白种人活体肾脏供者之间供者与受者关系的差异。
回顾了 1991 年至 2009 年期间在一家机构内所有成功的活体肾脏供者的数据。对供者和受者之间的关系进行分类，并进行组间比较。
研究样本包括 73 名（18%）非裔美国人和 324 名白种人活体肾脏供者。非裔美国人和白种人之间供者-受者关系的分布有显著差异。非裔美国供者与受者的关系更密切（88%比 74%，p=0.007）。非裔美国供者更可能参与子女向父母的捐赠，而不太可能参与父母向子女的捐赠或向非亲属捐赠。兄弟姐妹和配偶之间的捐赠在两组中相似。与非裔美国供者相比，白种供者与受者更可能没有关系。
非裔美国人和白种人活体肾脏供者之间的供者-受者关系存在差异。未来探索文化差异和家庭动态的研究可能为非裔美国人和白种人活体肾脏供者提供有针对性的招募策略。活体非亲属肾移植似乎是非裔美国人活体肾脏捐赠的一个潜在增长领域。
