Gao Fei, Yang Mei, Luo Chun Li, Pang Hua, Wu Xiao Hou
Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Acta Radiol. 2011 Jul 1;52(6):686-91. doi: 10.1258/ar.2011.100436. Epub 2011 Apr 20.
Renal parenchymal volume (RPV) is considered an important index for clinical decisions. However, normal values have not been established, which hinders the clinical application of RPV.
To test the accuracy and reproducibility of RPV and to investigate the normal values of RPV and kidney length as measured by non-enhanced multidetector computed tomography (CT).
An animal model study was performed to test the accuracy and repeatability of RPV measured by CT. RPV of porcine kidneys was measured by water displacement (actual values) and non-enhanced multidetector CT. Individual RPV and kidney length were measured by non-enhanced CT in patients with no clinical history of renal disease (n = 722). Patient height, age, weight, body surface area (BSA), and body mass index (BMI) were assessed before each patient's CT examination was performed.
RPV obtained by the CT method was within 2% of the RPV determined by the water displacement method. The normal values of RPV (M ± 1.96 standard deviation [SD]) were 145.72 ± 54.37 mL for men and 132.46 ± 41.94 mL for women. The normal values of kidney length (M ± 1.96 SD) were 10.27 ± 1.98 cm for men and 9.93 ± 1.58 cm for women. RPV did not significantly correlate with BSA or weight in women, but correlated significantly with height and age in both men and women. Of the assessed factors age, weight, height, BSA, and BMI, age, and height were the independent factors that best reflected RPV, in both men and women.
The present animal study results showed that non-enhanced multidetector CT findings accurately reflect the RPV. The subsequent study performed in humans showed that the RPV of the presently sampled Chinese population was lower than the commonly quoted reference values obtained from Western populations.
肾实质体积（RPV）被认为是临床决策的重要指标。然而，尚未确立其正常值，这阻碍了RPV的临床应用。
测试RPV的准确性和可重复性，并研究通过非增强型多排螺旋计算机断层扫描（CT）测量的RPV和肾脏长度的正常值。
进行动物模型研究以测试CT测量RPV的准确性和可重复性。通过排水法（实际值）和非增强型多排螺旋CT测量猪肾的RPV。对无肾脏疾病临床病史的患者（n = 722）进行非增强CT测量个体的RPV和肾脏长度。在每位患者进行CT检查前评估其身高、年龄、体重、体表面积（BSA）和体重指数（BMI）。
CT测量获得的RPV与排水法测定的RPV相差在2%以内。男性RPV的正常值（均值±1.96标准差[SD]）为145.72±54.37 mL，女性为132.46±41.94 mL。男性肾脏长度的正常值（均值±1.96 SD）为10.27±1.98 cm，女性为9.93±1.58 cm。女性的RPV与BSA或体重无显著相关性，但在男性和女性中均与身高和年龄显著相关。在评估的年龄、体重、身高、BSA和BMI因素中，年龄和身高是男性和女性中最能反映RPV的独立因素。
目前的动物研究结果表明，非增强型多排螺旋CT结果能准确反映RPV。随后在人类中进行的研究表明，目前抽样的中国人群的RPV低于从西方人群获得的常用参考值。
