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帕金森病的生物标志物。

Biomarkers for Parkinson's disease.

机构信息

The Michael J. Fox Foundation for Parkinson's Research, New York, NY 10004, USA.

出版信息

Sci Transl Med. 2011 Apr 20;3(79):79ps14. doi: 10.1126/scitranslmed.3002488.

DOI:10.1126/scitranslmed.3002488
PMID:21508309
Abstract

Biomarkers for detecting the early stages of Parkinson's disease (PD) could accelerate development of new treatments. Such biomarkers could be used to identify individuals at risk for developing PD, to improve early diagnosis, to track disease progression with precision, and to test the efficacy of new treatments. Although some progress has been made, there are many challenges associated with developing biomarkers for detecting PD in its earliest stages.

摘要

用于检测帕金森病(PD)早期阶段的生物标志物可以加速新疗法的开发。这些生物标志物可以用于识别有发展为 PD 风险的个体,以改善早期诊断,精确跟踪疾病进展,并测试新疗法的疗效。尽管已经取得了一些进展,但在开发用于检测 PD 早期阶段的生物标志物方面仍存在许多挑战。

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Biomarkers for Parkinson's disease.帕金森病的生物标志物。
Sci Transl Med. 2011 Apr 20;3(79):79ps14. doi: 10.1126/scitranslmed.3002488.
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Biomarkers for Parkinson's [corrected] disease: tools to assess Parkinson's disease onset and progression.帕金森病的生物标志物:评估帕金森病发病和进展的工具。 [已修正]
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The search for biomarkers in Parkinson's disease: a critical review.帕金森病生物标志物的探索:一项批判性综述
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Can we image premotor Parkinson disease?我们能否对运动前帕金森病进行成像?
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