El-Nashar Sherif A, Mariani Andrea
Division of Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Clin Obstet Gynecol. 2011 Jun;54(2):292-304. doi: 10.1097/GRF.0b013e31821ac635.
Carcinosarcoma is a rare but highly aggressive uterine malignancy. Pathologically, carcinosarcoma is a biphasic neoplasm composed of a mixture of malignant epithelial and mesenchymal components. A comprehensive approach for management is recommended with complete surgical staging to assess tumor dissemination followed by multimodal therapy with combinations of external beam irradiation or vaginal brachytherapy and systematic chemotherapy in patients with both early and advanced stage disease.
癌肉瘤是一种罕见但侵袭性很强的子宫恶性肿瘤。在病理上,癌肉瘤是一种双相性肿瘤,由恶性上皮成分和间叶成分混合组成。建议采用综合治疗方法,进行全面的手术分期以评估肿瘤播散情况,随后对早期和晚期患者采用外照射放疗或阴道近距离放疗与全身化疗联合的多模式治疗。