Russell R R
Hunterian Dental Research Unit, London Hospital Medical College, England.
Arch Oral Biol. 1990;35 Suppl:53S-58S. doi: 10.1016/0003-9969(90)90131-s.
Computer analysis of the primary amino acid sequences deduced from nucleotide sequences of cloned genes from Streptococcus mutans and Strep. downei was used to examine features of enzymes involved in formation and degradation of glucans. All 4 glucosyltransferases for which sequence data are available show a common structure characterized by a series of reiterated repeats in the carboxy-terminal one third of the molecule. These repeats are also found in Strep. mutans glucan-binding protein and resemble those found in enzymes from other bacteria with binding properties.
利用计算机对变形链球菌和唐氏链球菌克隆基因的核苷酸序列推导的一级氨基酸序列进行分析，以研究参与葡聚糖形成和降解的酶的特征。所有可获得序列数据的4种葡糖基转移酶都显示出一种共同结构，其特征是在分子的羧基末端三分之一处有一系列重复序列。这些重复序列也存在于变形链球菌葡聚糖结合蛋白中，并且类似于在其他具有结合特性的细菌的酶中发现的重复序列。
