Morresi-Hauf A T, Weber N, Gesierich W, Büsing C M
Institut für Pathologie, Asklepios Fachkliniken München-Gauting, Gauting.
Pneumologie. 2011 Jul;65(7):406-11. doi: 10.1055/s-0030-1256245. Epub 2011 Apr 21.
The papillary adenoma of the lung is a rare benign neoplasia with intraparenchymal localisation and is thus, in general, difficult to access for biopsy diagnosis. Due to the rarity of this lesion, the intra-operative histological diagnosis by frozen section may be problematic. We report on a 75-year-old male patient with a lung nodule, biopsied by means of bronchoscopy with TBNA. The tissue obtained was processed histologically as a cell block and examined microscopically. The diagnosis of a papillary adenoma was made. Our case is the first report on the diagnosis of a papillary adenoma of the lung by TBNA biopsy. For our patient with impaired lung function the diagnostic procedure described here represented a less invasive alternative to the diagnostic evaluation by surgery with intraoperative frozen section examination. This case shows that the TBNA biopsy combined with processing of the tissue as a cell block may represent a contribution to the appropriate management of the patients and serve as an aid for therapy planning.
肺乳头状腺瘤是一种罕见的良性肿瘤，位于肺实质内，因此一般难以进行活检诊断。由于这种病变罕见，术中通过冰冻切片进行组织学诊断可能存在问题。我们报告了一名75岁男性患者，其肺部结节通过支气管镜检查及经支气管针吸活检（TBNA）进行活检。所获得的组织作为细胞块进行组织学处理并显微镜检查。诊断为乳头状腺瘤。我们的病例是首例通过TBNA活检诊断肺乳头状腺瘤的报告。对于我们这位肺功能受损的患者，这里描述的诊断程序是一种比术中冰冻切片检查的手术诊断评估侵入性更小的替代方法。该病例表明，TBNA活检结合将组织作为细胞块处理可能有助于对患者进行适当管理，并辅助治疗规划。
